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SAP18 抗体

This anti-SAP18 antibody is a 兔 多克隆 antibody detecting SAP18 in WB 和 ELISA. Suitable for 人, 小鼠, 大鼠 和 犬.
产品编号 ABIN2461767
发货至: 中国

Quick Overview for SAP18 抗体 (ABIN2461767)

抗原

See all SAP18 抗体
SAP18 (Sin3A-Associated Protein, 18kDa (SAP18))

适用

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人, 小鼠, 大鼠, 犬

宿主

  • 22
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克隆类型

  • 24
  • 1
多克隆

标记

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This SAP18 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 纯化方法

    Antibody is purified by peptide affinity chromatography method.

    免疫原

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SAP18.
  • 应用备注

    SAP18 antibody can be used for detection of SAP18 by ELISA at 1:312500. SAP18 antibody can be used for detection of SAP18 by western blot at 0.125 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    浓度

    1 mg/mL

    缓冲液

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    注意事项

    As with any antibody avoid repeat freeze-thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store SAP18 antibody at -20 °C.
  • 抗原

    SAP18 (Sin3A-Associated Protein, 18kDa (SAP18))

    别名

    SAP18

    背景

    Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. SAP18 is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter.Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter.

    分子量

    18 kDa

    基因ID

    10284

    NCBI登录号

    NP_005861

    UniProt

    O00422
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