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JunB 抗体

This anti-JunB antibody is a 兔 多克隆 antibody detecting JunB in WB 和 ELISA. Suitable for 人 和 犬.
产品编号 ABIN2461653
发货至: 中国

Quick Overview for JunB 抗体 (ABIN2461653)

抗原

See all JunB (JUNB) 抗体
JunB (JUNB) (Jun B Proto-Oncogene (JUNB))

适用

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人, 犬

宿主

  • 116
  • 7
  • 1

克隆类型

  • 107
  • 17
多克隆

标记

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This JunB antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 纯化方法

    Antibody is purified by protein A chromatography method.

    免疫原

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human JUNB.
  • 应用备注

    JUNB antibody can be used for detection of JUNB by ELISA at 1:1562500. JUNB antibody can be used for detection of JUNB by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    浓度

    1 mg/mL

    缓冲液

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    注意事项

    As with any antibody avoid repeat freeze-thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store JUNB antibody at -20 °C.
  • 抗原

    JunB (JUNB) (Jun B Proto-Oncogene (JUNB))

    别名

    JUNB

    背景

    The c-Jun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus v-Jun oncogene. The c-Jun protein, along with c-Fos, is a component of the AP-1 transcriptional complex. c-Jun can form either Jun/Jun homodimers or Jun/Fos heterodimers via the leucine repeats in both proteins. Jun B and Jun D, have been shown to be almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in transcriptional activation, diverge. JunB is involved in many types of human carcinoma including T-cell lymphomas, CML,primary cutaneous lymphomas. Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B. JunB potentiates function of BRCA1 activation domain 1 (AD1) through a coiled-coil-mediated interaction.JunB is an important regulator of erythroid Differentiation.

    分子量

    36 kDa

    基因ID

    3726

    NCBI登录号

    NP_002220

    UniProt

    P17275
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