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EGR4 抗体

This anti-EGR4 antibody is a 兔 多克隆 antibody detecting EGR4 in WB 和 ELISA. Suitable for 人, 小鼠, 大鼠 和 犬.
产品编号 ABIN2461643
发货至: 中国

Quick Overview for EGR4 抗体 (ABIN2461643)

抗原

See all EGR4 抗体
EGR4 (Early Growth Response 4 (EGR4))

适用

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人, 小鼠, 大鼠, 犬

宿主

  • 18
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克隆类型

  • 19
多克隆

标记

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This EGR4 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 纯化方法

    Antibody is purified by peptide affinity chromatography method.

    免疫原

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human EGR4.
  • 应用备注

    EGR4 antibody can be used for detection of EGR4 by ELISA at 1:312500. EGR4 antibody can be used for detection of EGR4 by western blot at 0.0625 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    浓度

    1 mg/mL

    缓冲液

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    注意事项

    As with any antibody avoid repeat freeze-thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store EGR4 antibody at -20 °C.
  • 抗原

    EGR4 (Early Growth Response 4 (EGR4))

    别名

    EGR4

    背景

    The nerve growth factor-induced clone C (NGFI-C/EGR4) gene is a zinc-finger transcription factor that is rapidly induced by nerve growth factor in rat pheochromocytoma PC12 cells and by seizure in brain. NGFI-C/EGR4 is closely related to the previously described early response genes, nerve growth factor-induced clone A (NGFI-A or EGR1), EGR2, and EGR3. These four early response (immediate early) proteins all contain very similar zinc-finger DNA binding domains and five highly homologous subdomains. EGR-4 functionally cooperate with NFAT proteins and induce expression of IL-2 and TNFalpha. Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression.

    分子量

    51 kDa

    基因ID

    1961

    NCBI登录号

    NP_001956

    UniProt

    Q05215
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