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MID1 抗体

This anti-MID1 antibody is a 兔 多克隆 antibody detecting MID1 in WB 和 ELISA. Suitable for 人, 小鼠, 大鼠, 犬 和 斑马鱼.
产品编号 ABIN2461022
发货至: 中国

Quick Overview for MID1 抗体 (ABIN2461022)

抗原

See all MID1 抗体
MID1 (Midline 1 (MID1))

适用

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人, 小鼠, 大鼠, 犬, 斑马鱼

宿主

  • 49
  • 2

克隆类型

  • 50
  • 1
多克隆

标记

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  • 1
  • 1
  • 1
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  • 1
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  • 1
This MID1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 纯化方法

    Antibody is purified by protein A chromatography method.

    免疫原

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MID1.
  • 应用备注

    MID1 antibody can be used for detection of MID1 by ELISA at 1:312500. MID1 antibody can be used for detection of MID1 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    浓度

    1 mg/mL

    缓冲液

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    注意事项

    As with any antibody avoid repeat freeze-thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store MID1 antibody at -20 °C.
  • 抗原

    MID1 (Midline 1 (MID1))

    别名

    MID1

    背景

    MID1 is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Several different transcript variants are generated by alternate splicing, however, the full length nature of two variants has not been determined.

    分子量

    75 kDa, 75 kDa, 62 kDa

    基因ID

    4281

    NCBI登录号

    NP_000372

    UniProt

    O15344
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