ATP7A 抗体
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北京 101111
Quick Overview for ATP7A 抗体 (ABIN2460808)
抗原
See all ATP7A 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Antibody is purified by protein A chromatography method.
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免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ATP7A.
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应用备注
- ATP7A antibody can be used for detection of ATP7A by ELISA at 1:1562500. ATP7A antibody can be used for detection of ATP7A by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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浓度
- 1 mg/mL
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缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store ATP7A antibody at -20 °C.
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- ATP7A (ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A))
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别名
- ATP7A
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背景
- The ATP7A gene encodes the Menkes copper-translocating P-type ATPase, a ubiquitous protein that regulates the absorption of copper in the gastrointestinal tract. Inside cells, this protein has a dual function: it delivers copper to cuproenzymes in the Golgi compartment and effluxes excess copper. The trafficking mechanism and catalytic activity combine to facilitate absorption and intercellular transport of copper. Menkes disease, a systemic copper deficiency disorder, is caused by mutations in the ATP7A gene.
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分子量
- 30 kDa, 163 kDa, 70 kDa
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基因ID
- 538
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UniProt
- Q762B6
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途径
- Transition Metal Ion Homeostasis, Ribonucleoside Biosynthetic Process
抗原
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