POU4F3 抗体
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- 抗原 See all POU4F3 抗体
- POU4F3 (POU Domain, Class 4, Transcription Factor 3 (POU4F3))
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适用
- 人, 小鼠, 大鼠, 犬, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This POU4F3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 纯化方法
- Antibody is purified by protein A chromatography method.
- 免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human POU4F3.
- Top Product
- Discover our top product POU4F3 Primary Antibody
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- 应用备注
- POU4F3 antibody can be used for detection of POU4F3 by ELISA at 1:312500. POU4F3 antibody can be used for detection of POU4F3 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- 注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store POU4F3 antibody at -20 °C.
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- 抗原
- POU4F3 (POU Domain, Class 4, Transcription Factor 3 (POU4F3))
- 别名
- POU4F3 (POU4F3 产品)
- 别名
- POU4F3 antibody, BRN-3 antibody, BRN3 antibody, BRN3C antibody, DFNA15 antibody, BRN-3.1 antibody, brn-3c antibody, brn3.1 antibody, brn3c antibody, Brn3.1 antibody, Brn3c antibody, ddl antibody, dreidel antibody, POU class 4 homeobox 3 antibody, POU domain, class 4, transcription factor 3 antibody, POU4F3 antibody, Pou4f3 antibody, pou4f3 antibody
- 背景
- POU4F3 is capable of activating both BDNF and NT-3 promoters in inner ear sensory epithelial cell lines. Mutant POU4F3 loses most of its transcriptional activity and most of its ability to bind to DNA. The mutation causes autosomal-dominant nonsyndromic hearing loss and eventually leads to hair cell morbidity in affected family members.
- 分子量
- 37 kDa
- 基因ID
- 5459
- NCBI登录号
- NP_002691
- UniProt
- Q15319
- 途径
- Sensory Perception of Sound
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