POU4F3 抗体
Quick Overview for POU4F3 抗体 (ABIN2460646)
抗原
See all POU4F3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
纯化方法
- Antibody is purified by protein A chromatography method.
-
免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human POU4F3.
-
-
-
-
应用备注
- POU4F3 antibody can be used for detection of POU4F3 by ELISA at 1:312500. POU4F3 antibody can be used for detection of POU4F3 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
-
浓度
- 1 mg/mL
-
缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
-
注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store POU4F3 antibody at -20 °C.
-
-
- POU4F3 (POU Domain, Class 4, Transcription Factor 3 (POU4F3))
-
别名
- POU4F3
-
背景
- POU4F3 is capable of activating both BDNF and NT-3 promoters in inner ear sensory epithelial cell lines. Mutant POU4F3 loses most of its transcriptional activity and most of its ability to bind to DNA. The mutation causes autosomal-dominant nonsyndromic hearing loss and eventually leads to hair cell morbidity in affected family members.
-
分子量
- 37 kDa
-
基因ID
- 5459
-
NCBI登录号
- NP_002691
-
UniProt
- Q15319
-
途径
- Sensory Perception of Sound
抗原
-