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DMAP1 抗体

The 兔 多克隆 anti-DMAP1 antibody is suitable to detect DMAP1 in samples from 人, 小鼠 和 犬. It has been validated for WB 和 ELISA.
产品编号 ABIN2460614
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for DMAP1 抗体 (ABIN2460614)

抗原

See all DMAP1 抗体
DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))

适用

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人, 小鼠, 犬

宿主

  • 41
  • 4
  • 4

克隆类型

  • 33
  • 16
多克隆

标记

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This DMAP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 纯化方法

    Antibody is purified by protein A chromatography method.

    免疫原

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DMAP1.
  • 应用备注

    DMAP1 antibody can be used for detection of DMAP1 by ELISA at 1:62500. DMAP1 antibody can be used for detection of DMAP1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    浓度

    1 mg/mL

    缓冲液

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    注意事项

    As with any antibody avoid repeat freeze-thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store DMAP1 antibody at -20 °C.
  • 抗原

    DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))

    别名

    DMAP1

    背景

    DMAP1 is a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.

    分子量

    51 kDa, 53 kDa, 53 kDa

    基因ID

    55929

    NCBI登录号

    NP_001029196

    UniProt

    Q9NPF5
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