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SNW1 抗体

This anti-SNW1 antibody is a 兔 多克隆 antibody detecting SNW1 in WB, IHC 和 ELISA. Suitable for 人, 犬 和 大鼠.
产品编号 ABIN2460414
发货至: 中国

Quick Overview for SNW1 抗体 (ABIN2460414)

抗原

See all SNW1 抗体
SNW1 (SNW Domain Containing 1 (SNW1))

适用

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  • 1
人, 犬, 大鼠

宿主

  • 15

克隆类型

  • 15
多克隆

标记

  • 15
This SNW1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 纯化方法

    Antibody is purified by peptide affinity chromatography method.

    免疫原

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SKIIP.
  • 应用备注

    SKIIP antibody can be used for detection of SKIIP by ELISA at 1:62500. SKIIP antibody can be used for detection of SKIIP by western blot at 1.0-5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    浓度

    1 mg/mL

    缓冲液

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    注意事项

    As with any antibody avoid repeat freeze-thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store SKIIP antibody at -20 °C.
  • 抗原

    SNW1 (SNW Domain Containing 1 (SNW1))

    别名

    SKIIP

    背景

    SKIIP (Nuclear Protein SkiP, nuclear receptor coactivator NCoA-62, ski-interacting protein) is a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also interact with poly (A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.

    分子量

    61 kDa

    基因ID

    22938

    NCBI登录号

    NP_036377

    UniProt

    Q13573

    途径

    Retinoic Acid Receptor Signaling Pathway
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