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YAF2 抗体

YAF2 适用: 人, 犬 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2460230
发货至: 中国
  • 抗原 See all YAF2 抗体
    YAF2 (YY1 Associated Factor 2 (YAF2))
    适用
    • 21
    • 8
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 犬
    宿主
    • 24
    • 1
    克隆类型
    • 25
    多克隆
    标记
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This YAF2 antibody is un-conjugated
    应用范围
    • 14
    • 6
    • 5
    • 5
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    Antibody is purified by protein A chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human YAF2.
    Top Product
    Discover our top product YAF2 Primary Antibody
  • 应用备注
    YAF2 antibody can be used for detection of YAF2 by ELISA at 1:62500. YAF2 antibody can be used for detection of YAF2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store YAF2 antibody at -20 °C.
  • 抗原
    YAF2 (YY1 Associated Factor 2 (YAF2))
    别名
    YAF2 (YAF2 产品)
    别名
    MGC75686 antibody, YAF2 antibody, zgc:136577 antibody, si:ch211-155a11.5 antibody, 2810021M11Rik antibody, YY1 associated factor 2 antibody, YY1-associated factor 2 antibody, yaf2 antibody, YAF2 antibody, LOC100221270 antibody, Yaf2 antibody
    背景
    YAF2 interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. YAF2 contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1.The protein encoded by this gene interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. This gene product itself contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1. Multiple transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two have been confirmed to date.
    分子量
    20 kDa
    基因ID
    10138
    NCBI登录号
    NP_005739
    UniProt
    Q8IY57
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