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YAF2 抗体

This anti-YAF2 antibody is a 兔 多克隆 antibody detecting YAF2 in WB, IHC 和 ELISA. Suitable for 人 和 犬.
产品编号 ABIN2460230
发货至: 中国

Quick Overview for YAF2 抗体 (ABIN2460230)

抗原

See all YAF2 抗体
YAF2 (YY1 Associated Factor 2 (YAF2))

适用

  • 20
  • 10
  • 7
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
人, 犬

宿主

  • 27
  • 1

克隆类型

  • 28
多克隆

标记

  • 24
  • 2
  • 1
  • 1
This YAF2 antibody is un-conjugated

应用范围

  • 22
  • 13
  • 11
  • 9
  • 7
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 纯化方法

    Antibody is purified by protein A chromatography method.

    免疫原

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human YAF2.
  • 应用备注

    YAF2 antibody can be used for detection of YAF2 by ELISA at 1:62500. YAF2 antibody can be used for detection of YAF2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    浓度

    1 mg/mL

    缓冲液

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    注意事项

    As with any antibody avoid repeat freeze-thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store YAF2 antibody at -20 °C.
  • 抗原

    YAF2 (YY1 Associated Factor 2 (YAF2))

    别名

    YAF2

    背景

    YAF2 interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. YAF2 contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1.The protein encoded by this gene interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. This gene product itself contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1. Multiple transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two have been confirmed to date.

    分子量

    20 kDa

    基因ID

    10138

    NCBI登录号

    NP_005739

    UniProt

    Q8IY57
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