MXI1 抗体
Quick Overview for MXI1 抗体 (ABIN2460213)
抗原
See all MXI1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Antibody is purified by peptide affinity chromatography method.
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免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MXI1.
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anti-MAX Interactor 1 (MXI1) (AA 1-182) antibody
MXI1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1B10 unconjugated
anti-MAX Interactor 1 (MXI1) (Middle Region) antibodyMXI1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 斑马鱼, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-MAX Interactor 1 (MXI1) (AA 73-182) antibodyMXI1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F3 unconjugated
anti-MAX Interactor 1 (MXI1) (N-Term) antibodyMXI1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-MAX Interactor 1 (MXI1) (AA 75-173) antibodyMXI1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-MAX Interactor 1 (MXI1) (N-Term) antibodyMXI1 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MAX Interactor 1 (MXI1) (AA 176-225) antibodyMXI1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 斑马鱼, Pig, Bat, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MAX Interactor 1 (MXI1) (AA 215-264) antibodyMXI1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 斑马鱼, Pig, Bat, Hamster, 猴, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-MAX Interactor 1 (MXI1) (AA 170-295) antibodyMXI1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-MAX Interactor 1 (MXI1) (AA 76-295) antibodyMXI1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- MXI1 antibody can be used for detection of MXI1 by ELISA at 1:312500. MXI1 antibody can be used for detection of MXI1 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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浓度
- 1 mg/mL
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缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store MXI1 antibody at -20 °C.
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- MXI1 (MAX Interactor 1 (MXI1))
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别名
- MXI1
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背景
- Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The MXI1 gene encodes a transcriptional repressor protein thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in MXI1 are frequently found in patients with prostate tumors.Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.
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分子量
- 26 kDa, 21 kDa, 33 kDa
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基因ID
- 4601
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NCBI登录号
- NP_005953
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UniProt
- P50539
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途径
- Maintenance of Protein Location
抗原
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