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SPAG8 抗体

This anti-SPAG8 antibody is a 兔 多克隆 antibody detecting SPAG8 in ELISA 和 WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN2459942
发货至: 中国

Quick Overview for SPAG8 抗体 (ABIN2459942)

抗原

See all SPAG8 抗体
SPAG8 (Sperm Associated Antigen 8 (SPAG8))

适用

  • 50
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 47
  • 4

克隆类型

  • 49
  • 2
多克隆

标记

  • 22
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SPAG8 antibody is un-conjugated

应用范围

  • 24
  • 18
  • 13
  • 13
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
ELISA, Western Blotting (WB)
  • 纯化方法

    Antibody is purified by peptide affinity chromatography method.

    免疫原

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SPAG8.
  • 应用备注

    SPAG8 antibody can be used for detection of SPAG8 by ELISA at 1:62500. SPAG8 antibody can be used for detection of SPAG8 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    浓度

    1 mg/mL

    缓冲液

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    注意事项

    As with any antibody avoid repeat freeze-thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store SPAG8 antibody at -20 °C.
  • 抗原

    SPAG8 (Sperm Associated Antigen 8 (SPAG8))

    别名

    SPAG8

    背景

    The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. SPAG8 is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa.The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein encoded by this gene is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined.

    分子量

    53 kDa

    基因ID

    26206

    NCBI登录号

    NP_758516

    UniProt

    Q99932
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