Sphingomyelin Synthase 2 抗体
Quick Overview for Sphingomyelin Synthase 2 抗体 (ABIN2459622)
抗原
See all Sphingomyelin Synthase 2 (SGMS2) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Antibody is purified by peptide affinity chromatography method.
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免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SGMS2.
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anti-Sphingomyelin Synthase 2 (SGMS2) (AA 2-80) antibody
SGMS2 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 7D10 unconjugated
anti-Sphingomyelin Synthase 2 (SGMS2) (AA 1-79) antibodySGMS2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin Synthase 2 (SGMS2) (AA 338-365), (C-Term) antibodySGMS2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB24438 unconjugated
anti-Sphingomyelin Synthase 2 (SGMS2) antibodySGMS2 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin Synthase 2 (SGMS2) antibodySGMS2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin Synthase 2 (SGMS2) (AA 336-365), (C-Term) antibodySGMS2 适用: 人 WB, FACS, EIA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin Synthase 2 (SGMS2) (AA 71-120) antibodySGMS2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Bat, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin Synthase 2 (SGMS2) (N-Term) antibodySGMS2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- SGMS2 antibody can be used for detection of SGMS2 by ELISA at 1:312500. SGMS2 antibody can be used for detection of SGMS2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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浓度
- 1 mg/mL
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缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store SGMS2 antibody at -20 °C.
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- Sphingomyelin Synthase 2 (SGMS2)
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别名
- SGMS2
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背景
- SGMS2 is a bidirectional lipid cholinephosphotransferase capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and vice versa. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. SGMS2 directly and specifically recognizes the choline head group on the substrate. SGMS2 also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. SGMS2 does not function strictly as a SM synthase. SGMS2 is required for cell growth.Sphingomyelin (SM) is a major component of plasma membranes. It is preferentially concentrated in the outer leaflet and has a role in the formation of lipid rafts. SM synthases (EC 2.7.8.27), such as SGMS2, produce SM in the lumen of the Golgi and on the cell surface through the transfer of phosphocholine from phosphatidylcholine onto ceramide, yielding diacylglycerol as a side product (Huitema et al., 2004 [PubMed 14685263]).
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分子量
- 42 kDa
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基因ID
- 166929
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NCBI登录号
- NP_689834
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UniProt
- Q8NHU3
抗原
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