TMEM123 抗体
Quick Overview for TMEM123 抗体 (ABIN2459378)
抗原
See all TMEM123 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Antibody is purified by peptide affinity chromatography method.
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免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TMEM123.
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anti-Transmembrane Protein 123 (TMEM123) (AA 34-133) antibody
TMEM123 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F4 unconjugated
anti-Transmembrane Protein 123 (TMEM123) (AA 1-208) antibodyTMEM123 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Transmembrane Protein 123 (TMEM123) (C-Term) antibodyTMEM123 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 123 (TMEM123) (C-Term) antibodyTMEM123 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- TMEM123 antibody can be used for detection of TMEM123 by ELISA at 1:1562500. TMEM123 antibody can be used for detection of TMEM123 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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浓度
- 1 mg/mL
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缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store TMEM123 antibody at -20 °C.
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- TMEM123 (Transmembrane Protein 123 (TMEM123))
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别名
- TMEM123
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背景
- TMEM123 is a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. TMEM123 is proposed to function as a cell surface receptor that mediates cell death.This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.
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分子量
- 19 kDa
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基因ID
- 114908
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NCBI登录号
- NP_443164
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UniProt
- Q8N131
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途径
- Regulation of Cell Size
抗原
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