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TMEM123 抗体

This anti-TMEM123 antibody is a 兔 多克隆 antibody detecting TMEM123 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN2459378
发货至: 中国
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Quick Overview for TMEM123 抗体 (ABIN2459378)

抗原

See all TMEM123 抗体
TMEM123 (Transmembrane Protein 123 (TMEM123))

适用

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宿主

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克隆类型

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多克隆

标记

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This TMEM123 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 纯化方法

    Antibody is purified by peptide affinity chromatography method.

    免疫原

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TMEM123.
  • 应用备注

    TMEM123 antibody can be used for detection of TMEM123 by ELISA at 1:1562500. TMEM123 antibody can be used for detection of TMEM123 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    浓度

    1 mg/mL

    缓冲液

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    注意事项

    As with any antibody avoid repeat freeze-thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store TMEM123 antibody at -20 °C.
  • 抗原

    TMEM123 (Transmembrane Protein 123 (TMEM123))

    别名

    TMEM123

    背景

    TMEM123 is a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. TMEM123 is proposed to function as a cell surface receptor that mediates cell death.This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.

    分子量

    19 kDa

    基因ID

    114908

    NCBI登录号

    NP_443164

    UniProt

    Q8N131

    途径

    Regulation of Cell Size
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