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FCRLA 抗体

This 兔 多克隆 anti-FCRLA antibody specifically detects FCRLA in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN2459358
发货至: 中国
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Quick Overview for FCRLA 抗体 (ABIN2459358)

抗原

See all FCRLA 抗体
FCRLA (Fc Receptor-Like A (FCRLA))

适用

  • 11
  • 2

宿主

  • 7
  • 4
  • 2

克隆类型

  • 13
多克隆

标记

  • 13
This FCRLA antibody is un-conjugated

应用范围

  • 13
  • 3
  • 1
Western Blotting (WB), ELISA
  • 纯化方法

    Antibody is purified by peptide affinity chromatography method.

    免疫原

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FCRLA.
  • 应用备注

    FCRLA antibody can be used for detection of FCRLA by ELISA at 1:62500. FCRLA antibody can be used for detection of FCRLA by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    浓度

    1 mg/mL

    缓冲液

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    注意事项

    As with any antibody avoid repeat freeze-thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store FCRLA antibody at -20 °C.
  • 抗原

    FCRLA (Fc Receptor-Like A (FCRLA))

    别名

    FCRLA

    背景

    Receptors for the Fc fragment of IgG, or FCGRs, are cell surface glycoproteins of the Ig superfamily (IgSF). These receptors mediate phagocytosis of IgG-coated pathogens and promote activation of effector cells, leading to inflammatory responses and antibody-mediated cellular cytotoxicity. FCRLA may be implicated in B-cell differentiation and lymphomagenesis.Receptors for the Fc fragment of IgG, or FCGRs (see MIM 146790), are cell surface glycoproteins of the Ig superfamily (IgSF). These receptors mediate phagocytosis of IgG-coated pathogens and promote activation of effector cells, leading to inflammatory responses and antibody-mediated cellular cytotoxicity. All FCGR genes map to human chromosome 1. Additional genes in this region, including FREB, encode FCGR homologs that are selectively expressed in B cells and may be implicated in B-cell development and lymphomagenesis.

    分子量

    41 kDa

    基因ID

    84824

    NCBI登录号

    NP_116127

    UniProt

    Q7L513
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