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EDAR 抗体

This anti-EDAR antibody is a 兔 多克隆 antibody detecting EDAR in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN2459324
发货至: 中国

Quick Overview for EDAR 抗体 (ABIN2459324)

抗原

See all EDAR 抗体
EDAR (Ectodysplasin A Receptor (EDAR))

适用

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人, 小鼠, 大鼠

宿主

  • 24
  • 9
  • 2

克隆类型

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  • 11
  • 1
多克隆

标记

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This EDAR antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 纯化方法

    Antibody is purified by peptide affinity chromatography method.

    免疫原

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human EDAR.
  • 应用备注

    EDAR antibody can be used for detection of EDAR by ELISA at 1:12500. EDAR antibody can be used for detection of EDAR by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    浓度

    1 mg/mL

    缓冲液

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    注意事项

    As with any antibody avoid repeat freeze-thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store EDAR antibody at -20 °C.
  • 抗原

    EDAR (Ectodysplasin A Receptor (EDAR))

    别名

    EDAR

    背景

    EDAR is a member of the tumor necrosis factor receptor family. It is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in the gene encoding EDAR result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    分子量

    48 kDa

    基因ID

    10913

    NCBI登录号

    NP_071731

    UniProt

    Q9UNE0

    途径

    Tube Formation, Ubiquitin Proteasome Pathway
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