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XYLT2 抗体

This anti-XYLT2 antibody is a 兔 多克隆 antibody detecting XYLT2 in WB 和 ELISA. Suitable for 小鼠, 人, 犬 和 大鼠.
产品编号 ABIN2459323
发货至: 中国

Quick Overview for XYLT2 抗体 (ABIN2459323)

抗原

See all XYLT2 抗体
XYLT2 (Xylosyltransferase II (XYLT2))

适用

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小鼠, 人, 犬, 大鼠

宿主

  • 20

克隆类型

  • 20
多克隆

标记

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This XYLT2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 纯化方法

    Antibody is purified by peptide affinity chromatography method.

    免疫原

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human XYLT2.
  • 应用备注

    XYLT2 antibody can be used for detection of XYLT2 by ELISA at 1:312500. XYLT2 antibody can be used for detection of XYLT2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    浓度

    1 mg/mL

    缓冲液

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    注意事项

    As with any antibody avoid repeat freeze-thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store XYLT2 antibody at -20 °C.
  • 抗原

    XYLT2 (Xylosyltransferase II (XYLT2))

    别名

    XYLT2

    背景

    XYLT2 is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis.The protein encoded by this gene is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    分子量

    97 kDa

    基因ID

    64132

    NCBI登录号

    NP_071450

    UniProt

    Q9H1B5

    途径

    Glycosaminoglycan Metabolic Process
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