Protocadherin gamma Subfamily A, 4 (PCDHGA4) 抗体
Quick Overview for Protocadherin gamma Subfamily A, 4 (PCDHGA4) 抗体 (ABIN2459280)
抗原
See all Protocadherin gamma Subfamily A, 4 (PCDHGA4) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Antibody is purified by peptide affinity chromatography method.
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免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PCDHGA4.
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anti-Protocadherin gamma Subfamily A, 4 (PCDHGA4) (AA 249-298) antibody
PCDHGA4 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Protocadherin gamma Subfamily A, 4 (PCDHGA4) (AA 1-931) antibodyPCDHGA4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Protocadherin gamma Subfamily A, 4 (PCDHGA4) (N-Term) antibodyPCDHGA4 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Protocadherin gamma Subfamily A, 4 (PCDHGA4) (N-Term) antibodyPCDHGA4 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- PCDHGA4 antibody can be used for detection of PCDHGA4 by ELISA at 1:62500. PCDHGA4 antibody can be used for detection of PCDHGA4 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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浓度
- 1 mg/mL
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缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store PCDHGA4 antibody at -20 °C.
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- Protocadherin gamma Subfamily A, 4 (PCDHGA4)
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别名
- PCDHGA4
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背景
- PCDHGA4 is a single-pass type I membrane protein. It contains 6 cadherin domains. PCDHGA4 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
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分子量
- 86 kDa
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基因ID
- 56111
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NCBI登录号
- NP_114442
抗原
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