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Sep 15 抗体

This anti-Sep 15 antibody is a 兔 多克隆 antibody detecting Sep 15 in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN2459187
发货至: 中国

Quick Overview for Sep 15 抗体 (ABIN2459187)

抗原

See all Sep 15 (SEP15) 抗体
Sep 15 (SEP15) (15 KDa Selenoprotein (SEP15))

适用

  • 5
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 4
  • 1

克隆类型

  • 5
多克隆

标记

  • 5
This Sep 15 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA
  • 纯化方法

    Antibody is purified by peptide affinity chromatography method.

    免疫原

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human Septin 15.
  • 应用备注

    Septin 15 antibody can be used for detection of Septin 15 by ELISA at 1:312500. Septin 15 antibody can be used for detection of Septin 15 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    浓度

    1 mg/mL

    缓冲液

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    注意事项

    As with any antibody avoid repeat freeze-thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store Septin 15 antibody at -20 °C.
  • 抗原

    Sep 15 (SEP15) (15 KDa Selenoprotein (SEP15))

    背景

    SEP15 is a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. Studies in mouse suggest that this selenoprotein may have redox function and may be involved in the quality control of protein folding. The gene that encodes the protein is localized on chromosome 1p31, a genetic locus commonly mutated or deleted in human cancers. This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies in mouse suggest that this selenoprotein may have redox function and may be involved in the quality control of protein folding. This gene is localized on chromosome 1p31, a genetic locus commonly mutated or deleted in human cancers. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

    分子量

    15 kDa

    基因ID

    9403

    NCBI登录号

    NP_004252

    UniProt

    O60613
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