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DPF3 抗体

The 兔 多克隆 anti-DPF3 antibody (ABIN2458080) specifically detects DPF3 in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN2458080
发货至: 中国
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Quick Overview for DPF3 抗体 (ABIN2458080)

抗原

See all DPF3 抗体
DPF3 (D4, Zinc and Double PHD Fingers, Family 3 (DPF3))

适用

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人, 小鼠, 大鼠

宿主

  • 42

克隆类型

  • 42
多克隆

标记

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This DPF3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 纯化方法

    Antibody is purified by peptide affinity chromatography method.

    免疫原

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DPF3.
  • 应用备注

    DPF3 antibody can be used for detection of DPF3 by ELISA at 1:12500. DPF3 antibody can be used for detection of DPF3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    浓度

    1 mg/mL

    缓冲液

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    注意事项

    As with any antibody avoid repeat freeze-thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store DPF3 antibody at -20 °C.
  • 抗原

    DPF3 (D4, Zinc and Double PHD Fingers, Family 3 (DPF3))

    别名

    DPF3

    背景

    DPF3 is a muscle-specific component of the BAF complex, a multiprotein complex involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). DPF3 specifically binds acetylated lysines on histone 3 and 4 (H3K14ac, H3K9ac, H4K5ac, H4K8ac, H4K12ac, H4K16ac). In the complex, it acts as a tissue-specific anchor between histone acetylations and methylations and chromatin remodeling. It thereby probably plays an essential role in heart and skeletal muscle development.

    分子量

    40 kDa

    基因ID

    8110

    NCBI登录号

    NP_036206

    UniProt

    Q92784
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