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RRM2 抗体 (C-Term)

There is 1 publication for this product available. The 兔 多克隆 anti-RRM2 antibody is suitable to detect RRM2 in samples from 人, 小鼠, 大鼠 和 非洲爪蟾. It has been validated for WB 和 IF.
产品编号 ABIN2452118
发货至: 中国
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Quick Overview for RRM2 抗体 (C-Term) (ABIN2452118)

抗原

See all RRM2 抗体
RRM2 (Ribonucleotide Reductase M2 (RRM2))

适用

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人, 小鼠, 大鼠, 非洲爪蟾

宿主

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克隆类型

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  • 1
多克隆

标记

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This RRM2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    C-Term

    交叉反应 (详细)

    Not tested in other species.

    纯化方法

    Affinity-purified with the immunogen peptide

    过滤

    Sterile filtered

    免疫原

    C-terminal peptide of Human and Mouse RRM2, C-TENSFTLDADF, conjugated with KLH
  • 应用备注

    1) Western blotting: ~ 1/1,000 dilution
    Not tested for other applications

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS (x1), 50 % glycerol. Azide and carrier free.

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Upon receipt aliquot and store at -20 C
  • Takada, Shibata, Hiraoka, Masuda: "Identification of ribonucleotide reductase protein R1 as an activator of microtubule nucleation in Xenopus egg mitotic extracts." in: Molecular biology of the cell, Vol. 11, Issue 12, pp. 4173-87, (2000) (PubMed).

  • 抗原

    RRM2 (Ribonucleotide Reductase M2 (RRM2))

    别名

    RRM2 / RNR-R2

    背景

    Betag Ribonucleoside-diphosphate reductase subunit M2 (RRM2, 389 aa, 45 kDa) also known as ribonucleotide reductase subunit R2 (RNR-R2), is a rate-limiting subunit of an enzyme that catalyzes the formation of deoxyribonucleotides from ribonucleotides. Deoxyribonucleotides in turn are used in the synthesis of DNA. The reaction catalyzed by RNR is strictly conserved in all living organisms. Furthermore RNR plays a critical role in regulating the total rate of DNA synthesis so that DNA to cell mass is maintained at a constant ratio during cell division and DNA repair.

    UniProt

    P31350

    途径

    Mitotic G1-G1/S Phases
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