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PSMD8 抗体

PSMD8 适用: Saccharomyces cerevisiae WB, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2452112
发货至: 中国
  • 抗原 See all PSMD8 抗体
    PSMD8 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8))
    适用
    • 30
    • 24
    • 22
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    Saccharomyces cerevisiae
    宿主
    • 27
    • 3
    克隆类型
    • 29
    • 1
    多克隆
    标记
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This PSMD8 antibody is un-conjugated
    应用范围
    • 26
    • 13
    • 7
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    纯化方法
    Affinity purified
    免疫原
    Recombinant yeast Rpn12 expressed in E. coli
    亚型
    IgG
    Top Product
    Discover our top product PSMD8 Primary Antibody
  • 应用备注
    1) Western blotting: 1/5,000~1/10,000
    2) Immunoprecipitation
    Other applications have not been tested.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, 1 mg/mL BSA, 0.09 % sodium azide, 50 % glycerol
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • Tone, Tanahashi, Tanaka, Fujimuro, Yokosawa, Toh-e: "Nob1p, a new essential protein, associates with the 26S proteasome of growing saccharomyces cerevisiae cells." in: Gene, Vol. 243, Issue 1-2, pp. 37-45, (2000) (PubMed).

    Takeuchi, Toh-e et al.: "Genetic evidence for interaction between components of the yeast 26S proteasome: combination of a mutation in RPN12 (a lid component gene) with mutations in RPT1 (an ATPase gene) causes synthetic ..." in: Molecular & general genetics : MGG, Vol. 262, Issue 1, pp. 145-53, (1999) (PubMed).

    Hershko, Ciechanover: "The ubiquitin system." in: Annual review of biochemistry, Vol. 67, pp. 425-79, (1998) (PubMed).

  • 抗原
    PSMD8 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8))
    别名
    Rpn12 (PSMD8 产品)
    别名
    HIP6 antibody, HYPF antibody, Nin1p antibody, Rpn12 antibody, S14 antibody, p31 antibody, hip6 antibody, hypf antibody, nin1p antibody, rpn12 antibody, psmd8b antibody, 6720456J22Rik antibody, AA407360 antibody, AL033291 antibody, AL033322 antibody, AL033323 antibody, C76433 antibody, psmd8 antibody, psmd8a antibody, fa93g07 antibody, fb17c09 antibody, fb49a10 antibody, zgc:86762 antibody, wu:fa93g07 antibody, wu:fb17c09 antibody, wu:fb49a10 antibody, PSMD8 antibody, proteasome 26S subunit, non-ATPase 8 antibody, proteasome 26S subunit, non-ATPase 8 S homeolog antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 antibody, proteasome 26S subunit, non-ATPase 8 L homeolog antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 pseudogene antibody, PSMD8 antibody, psmd8.S antibody, Psmd8 antibody, psmd8.L antibody, psmd8 antibody, LOC468490 antibody
    背景
    Background: The 26 S proteasome is a protein complex with a molecular mass of 2,000 kDa. It is essential not only for eliminating damaged or misfolded proteins but also for degrading short lived regulatory proteins involved in cell cycle regulation, DNA repair, signal transduction, apoptosis, and metabolic regulation. The 26S proteasome is composed of the 20S core particle (CP) and the 19S regulatory particle (RP). The RP is further subdivided into lid and base sub-complexes. Rpn12 is one of the non-ATPase subunits of the lid. Rpn12 interacts with an ATPase subunit, Rpt1, of the base. Rpn12, Rpt1 double mutant becomes lethal, suggesting a strong interaction between Rpn12 and Rpt1. In the double mutant cells, the function of the 26S proteasome is completely eliminated.
    途径
    Mitotic G1-G1/S Phases, DNA Replication, Proton Transport, Synthesis of DNA, SARS-CoV-2 Protein Interactome, Ubiquitin Proteasome Pathway
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