PSMD8 抗体
(3 references)Quick Overview for PSMD8 抗体 (ABIN2452112)
抗原
See all PSMD8 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity purified
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免疫原
- Recombinant yeast Rpn12 expressed in E. coli
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亚型
- IgG
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anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8) antibody
PSMD8 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8) (AA 101-350), (Regulatory Subunit 8) antibodyPSMD8 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8) (AA 1-257) antibodyPSMD8 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8) (AA 101-350) antibodyPSMD8 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8) antibodyPSMD8 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8) (AA 4-232) antibodyPSMD8 适用: 人, 小鼠, 大鼠 WB, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8) (C-Term) antibodyPSMD8 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8) antibodyPSMD8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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1) Western blotting: 1/5,000~1/10,000
2) Immunoprecipitation
Other applications have not been tested. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, 1 mg/mL BSA, 0.09 % sodium azide, 50 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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: "Nob1p, a new essential protein, associates with the 26S proteasome of growing saccharomyces cerevisiae cells." in: Gene, Vol. 243, Issue 1-2, pp. 37-45, (2000) (PubMed).
: "Genetic evidence for interaction between components of the yeast 26S proteasome: combination of a mutation in RPN12 (a lid component gene) with mutations in RPT1 (an ATPase gene) causes synthetic ..." in: Molecular & general genetics : MGG, Vol. 262, Issue 1, pp. 145-53, (1999) (PubMed).
: "The ubiquitin system." in: Annual review of biochemistry, Vol. 67, pp. 425-79, (1998) (PubMed).
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: "Nob1p, a new essential protein, associates with the 26S proteasome of growing saccharomyces cerevisiae cells." in: Gene, Vol. 243, Issue 1-2, pp. 37-45, (2000) (PubMed).
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- PSMD8 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8))
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别名
- Rpn12
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背景
- Background: The 26 S proteasome is a protein complex with a molecular mass of 2,000 kDa. It is essential not only for eliminating damaged or misfolded proteins but also for degrading short lived regulatory proteins involved in cell cycle regulation, DNA repair, signal transduction, apoptosis, and metabolic regulation. The 26S proteasome is composed of the 20S core particle (CP) and the 19S regulatory particle (RP). The RP is further subdivided into lid and base sub-complexes. Rpn12 is one of the non-ATPase subunits of the lid. Rpn12 interacts with an ATPase subunit, Rpt1, of the base. Rpn12, Rpt1 double mutant becomes lethal, suggesting a strong interaction between Rpn12 and Rpt1. In the double mutant cells, the function of the 26S proteasome is completely eliminated.
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途径
- Mitotic G1-G1/S Phases, DNA Replication, Proton Transport, Synthesis of DNA, SARS-CoV-2 Protein Interactome, Ubiquitin Proteasome Pathway
抗原
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