NOB1 抗体
Quick Overview for NOB1 抗体 (ABIN2452059)
抗原
See all NOB1 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Product: Rabbit polyclonal antibody affinity purified with recombinant Nob1p
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纯化方法
- Affinity purified
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免疫原
- Recombinant yeast Nob1p expressed in E. coli
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亚型
- IgG
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应用备注
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1) Western blotting: ~400 fold dilution
2) Immunoprecipitation Not tested for other applications. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, 1 mg/mL BSA as carrier, 0.09 % sodium azide, 50 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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: "Nob1p is required for biogenesis of the 26S proteasome and degraded upon its maturation in Saccharomyces cerevisiae." in: Genes & development, Vol. 16, Issue 24, pp. 3142-57, (2002) (PubMed).
: "Nob1p, a new essential protein, associates with the 26S proteasome of growing saccharomyces cerevisiae cells." in: Gene, Vol. 243, Issue 1-2, pp. 37-45, (2000) (PubMed).
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: "Nob1p is required for biogenesis of the 26S proteasome and degraded upon its maturation in Saccharomyces cerevisiae." in: Genes & development, Vol. 16, Issue 24, pp. 3142-57, (2002) (PubMed).
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- NOB1 (RNA-Binding Protein NOB1 (NOB1))
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别名
- Nob1
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背景
- Background: The 26 S proteasome is a protein complex with a molecular mass of 2,000 kDa. It is essential not only for eliminating damaged or misfolded proteins but also for degrading short lived regulatory proteins involved in cell cycle regulation, DNA repair, signal transduction, apoptosis, and metabolic regulation. Nob1p is essential nuclear protein required for biogenesis of the 26S proteasome. Nob1p is speculated to serve as a chaperone to join the 20S proteasome with the 19S regulatory particle in the nucleus and to be degraded upon the maturation of the 26S proteasome. Nob1p is composed of 459 amino acid residues.
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途径
- Protein targeting to Nucleus
抗原
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