Nas6/p28 抗体
There are 3+ publications for this product available. The 兔 多克隆 anti-Nas6/p28 antibody is suitable to detect Nas6/p28 in samples from Saccharomyces cerevisiae. It has been validated for IP 和 WB.
1 image
(3 references)
产品编号 ABIN2452055
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Quick Overview for Nas6/p28 抗体 (ABIN2452055)
抗原
Nas6/p28
适用
Saccharomyces cerevisiae
宿主
兔
克隆类型
多克隆
应用范围
Immunoprecipitation (IP), Western Blotting (WB)
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交叉反应 （详细）
- Not tested in other species.
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纯化方法
- Affinity purified
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免疫原
- Recombinant yeast Nas6 expressed in E. coli
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亚型
- IgG
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应用备注
- 1) Western blotting: 5000 fold dilution
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, 1 mg/mL BSA, 0.09 % sodium azide, 50 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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: "Multiple proteasome-interacting proteins assist the assembly of the yeast 19S regulatory particle." in: Cell, Vol. 137, Issue 5, pp. 900-13, (2009) (PubMed).
: "cDNA cloning and functional analysis of p28 (Nas6p) and p40.5 (Nas7p), two novel regulatory subunits of the 26S proteasome." in: Gene, Vol. 216, Issue 1, pp. 113-22, (1998) (PubMed).
: "The ubiquitin system." in: Annual review of biochemistry, Vol. 67, pp. 425-79, (1998) (PubMed).
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- Nas6/p28
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背景
- Background: The 26 S proteasome is a protein complex with a molecular mass of 2,000 kDa. It is essential not only for eliminating damaged or misfolded proteins but also for degrading short lived regulatory proteins involved in cell cycle regulation, DNA repair, signal transduction, apoptosis, and metabolic regulation. The 26S proteasome is composed of the 20S core particle (CP) and the 19S regulatory particle (RP). The RP is further subdivided into lid and base sub-complexes. NAS6 (p28) is a proteasome-interacting protein which acts as a chaperon to assemble the base sub-complex of the 19S RP. NAS6 is composed of 226 amino acid residues with calculated molecular masses of 24.4kD.
抗原
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