KPNA4 抗体 (full length)
Quick Overview for KPNA4 抗体 (full length) (ABIN2452037)
抗原
See all KPNA4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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    - 
                                            抗原表位
- full length
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                                            特异性
- Reactive with human, simian, mouse, rat, hamster, canine and bovine importin a3. This antibody doesn't recognize other importin a family including a4.
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                                            产品特性
- The antibody was purified from the serum-free cultured medium of the hybridoma under mild conditions by proprietary chromatography processes.
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                                            纯化方法
- Purified
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                                            过滤
- Sterile filtered
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                                            免疫原
- Recombinant mouse importin a3 /KPNA4/ Qip 1 (full length)
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                                            亚型
- IgG2a kappa
 
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                                            应用备注
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                        1. Western blotting: 250~500 fold dilution
 2. ELISA
 This antibody doesn't work for immunostaining and immunoprecipitation.
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            浓度
- 1 mg/mL
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                                            缓冲液
- PBS, 50 % glycerol
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                                            储存液
- Azide free
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                                            储存条件
- -20 °C/-80 °C
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                                            储存方法
- -20 C (For long term storage: -70 C)
 
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    - 
                                            : "Triggering neural differentiation of ES cells by subtype switching of importin-alpha."    in: Nature cell biology, Vol. 9, Issue 1, pp. 72-9, (2007)         (PubMed).        
 : "Nucleocytoplasmic protein traffic and its significance to cell function." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 5, Issue 10, pp. 777-87, (2000) (PubMed).
 : "Differential modes of nuclear localization signal (NLS) recognition by three distinct classes of NLS receptors." in: The Journal of biological chemistry, Vol. 272, Issue 42, pp. 26375-81, (1997) (PubMed).
 
 
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                                            : "Triggering neural differentiation of ES cells by subtype switching of importin-alpha."    in: Nature cell biology, Vol. 9, Issue 1, pp. 72-9, (2007)         (PubMed).        
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    - KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))
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                                            别名
- Importin alpha 3 / Qip1KPNA4
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                                            背景
- Importin a proteins play a pivotal role in the import of proteins from the cytoplasm to the nucleus. Importin a proteins shuttle between nucleus and cytoplasm, bind nuclear localization signal (NLS)-bearing proteins, and mediate the protein import into the nucleus with importin b. Several importin a isotypes have been identified, each exhibiting differential recognition and nuclear transport, probably via preferential binding to a particular NLS. The importin a3 (KPNA4, Qip1) is a member of the importin a family of proteins belonging to the Qip1 subfamily.
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                                            途径
- Protein targeting to Nucleus
 抗原
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