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KPNA4 抗体 (full length)

Cited in 3+ publications. This anti-KPNA4 antibody is a 大鼠 单克隆 antibody detecting KPNA4 in WB 和 ELISA. Suitable for 小鼠.
产品编号 ABIN2452037
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for KPNA4 抗体 (full length) (ABIN2452037)

抗原

See all KPNA4 抗体
KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))

适用

  • 41
  • 37
  • 15
  • 5
  • 4
  • 4
  • 4
  • 4
  • 1
  • 1
  • 1
小鼠

宿主

  • 51
  • 1
大鼠

克隆类型

  • 52
单克隆

标记

  • 22
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This KPNA4 antibody is un-conjugated

应用范围

  • 39
  • 19
  • 14
  • 13
  • 11
  • 9
  • 7
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA

克隆位点

3D10
  • 抗原表位

    • 15
    • 7
    • 6
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    full length

    特异性

    Reactive with human, simian, mouse, rat, hamster, canine and bovine importin a3. This antibody doesn't recognize other importin a family including a4.

    产品特性

    The antibody was purified from the serum-free cultured medium of the hybridoma under mild conditions by proprietary chromatography processes.

    纯化方法

    Purified

    过滤

    Sterile filtered

    免疫原

    Recombinant mouse importin a3 /KPNA4/ Qip 1 (full length)

    亚型

    IgG2a kappa
  • 应用备注

    1. Western blotting: 250~500 fold dilution
    2. ELISA
    This antibody doesn't work for immunostaining and immunoprecipitation.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol

    储存液

    Azide free

    储存条件

    -20 °C/-80 °C

    储存方法

    -20 C (For long term storage: -70 C)
  • Yasuhara, Shibazaki, Tanaka, Nagai, Kamikawa, Oe, Asally, Kamachi, Kondoh, Yoneda: "Triggering neural differentiation of ES cells by subtype switching of importin-alpha." in: Nature cell biology, Vol. 9, Issue 1, pp. 72-9, (2007) (PubMed).

    Yoneda: "Nucleocytoplasmic protein traffic and its significance to cell function." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 5, Issue 10, pp. 777-87, (2000) (PubMed).

    Miyamoto, Imamoto, Sekimoto, Tachibana, Seki, Tada, Enomoto, Yoneda: "Differential modes of nuclear localization signal (NLS) recognition by three distinct classes of NLS receptors." in: The Journal of biological chemistry, Vol. 272, Issue 42, pp. 26375-81, (1997) (PubMed).

  • 抗原

    KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))

    别名

    Importin alpha 3 / Qip1KPNA4

    背景

    Importin a proteins play a pivotal role in the import of proteins from the cytoplasm to the nucleus. Importin a proteins shuttle between nucleus and cytoplasm, bind nuclear localization signal (NLS)-bearing proteins, and mediate the protein import into the nucleus with importin b. Several importin a isotypes have been identified, each exhibiting differential recognition and nuclear transport, probably via preferential binding to a particular NLS. The importin a3 (KPNA4, Qip1) is a member of the importin a family of proteins belonging to the Qip1 subfamily.

    途径

    Protein targeting to Nucleus
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