CBX3 抗体 (C-Term)
Quick Overview for CBX3 抗体 (C-Term) (ABIN2452035)
抗原
See all CBX3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应 (详细)
- Expected to react with chicken, Xenopus, Drosophila, and zebra fish orthologs due to the sequence identity of the immunogen.
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产品特性
- The product is prepared by immunizing rabbit with the synthetic peptide WHSCPEDEAQ-C corresponding to the C-terminal sequence of human HP1γ and purified by affinity purification with the peptide. The antiserum preparation has been directed by Prof. T. Haraguchi.
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纯化方法
- Affinity purified
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过滤
- Sterile filtered
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亚型
- IgG
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应用备注
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1) Western blotting: 1/2,000~1/10,000
2) Immunofluorescence staining
3) Chromatin immunoprecipitation (ChIP) -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.75 mg/mL
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缓冲液
- 0.12 M sodium phosphate buffer ( pH 7.4), 50 % glycerol
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储存液
- Azide free
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储存条件
- -20 °C/-80 °C
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储存方法
- -20 C (For long term storage: -70 C)
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: "The Heterochromatin Protein 1 family." in: Genome biology, Vol. 7, Issue 7, pp. 228, (2007) (PubMed).
: "The assembly and maintenance of heterochromatin initiated by transgene repeats are independent of the RNA interference pathway in mammalian cells." in: Molecular and cellular biology, Vol. 26, Issue 11, pp. 4028-40, (2006) (PubMed).
: "Interaction of the chromatin compaction-inducing domain (LR domain) of Ki-67 antigen with HP1 proteins." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 7, Issue 12, pp. 1231-42, (2002) (PubMed).
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: "The Heterochromatin Protein 1 family." in: Genome biology, Vol. 7, Issue 7, pp. 228, (2007) (PubMed).
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- CBX3 (Chromobox Homolog 3 (CBX3))
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别名
- HP1gamma/CBX3
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背景
- Heterochromatin protein 1 (HP1) is a major component of heterochromatin which plays a role in assembly of various proteins on chromatin and gene silencing. The HP1 family is evolutionally conserved, with members in fungi, plants and animals but not prokaryotes, and there are multiple members within the same species. The HP1 family proteins are encoded by a class of genes known as the chromobox (CBX) genes. In humans, HP1γ is encoded by the Chromobox homolog 3 (CBX3) gene. HP1γ has been observed to interact directly or indirectly with several non-histone proteins with a wide variety of functions.
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UniProt
- Q13185
抗原
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