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CBX1 抗体 (AA 176-185)

This anti-CBX1 antibody is a 兔 多克隆 antibody detecting CBX1 in WB, IF 和 ChIP-seq. Suitable for 人 和 Hamster. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN2452034
发货至: 中国

Quick Overview for CBX1 抗体 (AA 176-185) (ABIN2452034)

抗原

See all CBX1 抗体
CBX1 (Chromobox Homolog 1 (CBX1))

适用

  • 44
  • 20
  • 17
  • 7
  • 7
  • 6
  • 5
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
人, Hamster

宿主

  • 33
  • 8
  • 2
  • 1

克隆类型

  • 32
  • 11
  • 1
多克隆

标记

  • 31
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CBX1 antibody is un-conjugated

应用范围

  • 31
  • 24
  • 10
  • 9
  • 6
  • 5
  • 5
  • 4
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), ChIP DNA-Sequencing (ChIP-seq)
  • 抗原表位

    • 8
    • 7
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 176-185

    交叉反应 (详细)

    Expected to react with mouse, chicken, zebra fish, Xenopus, Drosophila orthologs due to the sequence identity of the immunogen.

    产品特性

    The product is prepared by immunizing rabbit with the synthetic peptide CNEDDDKKDDKN including the C-terminal sequence (176-185) of human HP1beta and purified by affinity purification with the peptide. The antiserum was prepared by the direction of Prof. T. Haraguchi.

    纯化方法

    Affinity purified

    过滤

    Sterile filtered

    亚型

    IgG
  • 应用备注

    1) Western blotting: 1/2,000~1/10,000
    2) Immunofluorescence staining
    3) Chromatin immunoprecipitation (ChIP)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.44 mg/mL

    缓冲液

    0.12 M sodium phosphate buffer ( pH 7.4), 50 % glycerol

    储存液

    Azide free

    储存条件

    -20 °C/-80 °C

    储存方法

    -20 C (For long term storage: -70 C)
  • Lomberk, Wallrath, Urrutia: "The Heterochromatin Protein 1 family." in: Genome biology, Vol. 7, Issue 7, pp. 228, (2007) (PubMed).

    Wang, Koyama, Nishida, Haraguchi, Reith, Tsukamoto: "The assembly and maintenance of heterochromatin initiated by transgene repeats are independent of the RNA interference pathway in mammalian cells." in: Molecular and cellular biology, Vol. 26, Issue 11, pp. 4028-40, (2006) (PubMed).

    Kametaka, Takagi, Hayakawa, Haraguchi, Hiraoka, Yoneda: "Interaction of the chromatin compaction-inducing domain (LR domain) of Ki-67 antigen with HP1 proteins." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 7, Issue 12, pp. 1231-42, (2002) (PubMed).

  • 抗原

    CBX1 (Chromobox Homolog 1 (CBX1))

    别名

    HP1 beta/cbx1

    背景

    Heterochromatin protein 1 (HP1) is a major component of heterochromatin which plays a role in assembly of various proteins on chromatin and gene silencing. The HP1 family is evolutionally conserved, with members in fungi, plants and animals but not prokaryotes, and there are multiple members within the same species. The HP1 family proteins are encoded by a class of genes known as the chromobox (CBX) genes. In humans, HP1beta is encoded by the Chromobox homolog 1 (CBX1) gene located on chromosome 17q21.32. HP1beta has been observed to interact directly or indirectly with several non-histone proteins with a wide variety of functions.

    UniProt

    P83916
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