HCV Core Protein 抗体 (AA 13-124, AA 369-704) (Biotin)
(5 references)Quick Overview for HCV Core Protein 抗体 (AA 13-124, AA 369-704) (Biotin) (ABIN2451996)
抗原
See all HCV Core Protein (HCV C) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 13-124, AA 369-704
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特异性
- Specific to human HCV core antigen of genotype 1b.
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交叉反应 （详细）
- Not tested in other genotypes.
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过滤
- Sterile filtered
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免疫原
- A part of the core region (nucleotides 369-704, aa 13-124) of HCV C expressed in E. coli
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亚型
- IgG2a kappa
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anti-Hepatitis C Virus Core Protein (HCV C) (AA 13-124), (AA 369-704) antibody (FITC)
HCV C 适用: Hepatitis C Virus (HCV) IF, IHC 宿主: 小鼠 Monoclonal H6-29 FITC
anti-Hepatitis C Virus Core Protein (HCV C) antibodyHCV C 适用: Hepatitis C Virus (HCV) WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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1. Western blotting
2. Immunohistochemistry
3. Immunofluorescence staining
4. ELISA -
说明
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Conjugate: Bitin conjugated, [biotin] / [IgG] = 6.6
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.7 mg/mL
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缓冲液
- PBS, 50 % glycerol
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储存液
- Azide free
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储存条件
- -20 °C
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: "Molecular virology of hepatitis C virus (HCV): 2006 update." in: International journal of medical sciences, Vol. 3, Issue 2, pp. 29-34, (2006) (PubMed).
: "Production of nonstructural proteins of hepatitis C virus requires a putative viral protease encoded by NS3." in: Virology, Vol. 198, Issue 2, pp. 636-44, (1994) (PubMed).
: "Immunohistochemical detection of hepatitis C virus-infected hepatocytes in chronic liver disease with monoclonal antibodies to core, envelope and NS3 regions of the hepatitis C virus genome." in: Hepatology (Baltimore, Md.), Vol. 16, Issue 2, pp. 306-11, (1992) (PubMed).
: "Structure and organization of the hepatitis C virus genome isolated from human carriers." in: Journal of virology, Vol. 65, Issue 3, pp. 1105-13, (1991) (PubMed).
: "Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 24, pp. 9524-8, (1991) (PubMed).
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: "Molecular virology of hepatitis C virus (HCV): 2006 update." in: International journal of medical sciences, Vol. 3, Issue 2, pp. 29-34, (2006) (PubMed).
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- HCV Core Protein (HCV C) (Hepatitis C Virus Core Protein (HCV C))
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别名
- HCV Core Protein
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物质类
- Viral Protein
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背景
- Hepatitis C virus (HCV) is a small (55-65 nm in size), enveloped, positive sense single-stranded RNA virus in the family Flaviviridae and the principal cause of parenteral non-A, non-B hepatitis. The virus genome consists of a single open reading frame of approximately 9,4 kb which encodes a single polyprotein of about 3,010 amino acids. The polyprotein is processed by host cell and viral proteases into four structural proteins (core, envelope1 and 2, and p7) and six non-structural proteins (NS2, 3, 4a, 4b, 5a, and 5b) necessary for viral replication. HCV core protein is not only a component of nucleocapsid but also has multiple functions and is a pathogenic factor for hepatitis. It also participates in some cellular processes, including transcriptional regulation and cellular transduction. HCV core antigen is used as diagnostic marker for HCV infection.
抗原
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