Intermolecular Guanine Quadruplex DNA 抗体
The 小鼠 单克隆 anti-Intermolecular Guanine Quadruplex DNA antibody (Clone 1H6) (ABIN2443989) specifically detects Intermolecular Guanine Quadruplex DNA in ELISA, IF, ICC 和 IHC.
The antibody is reactive with Synthetic samples.
产品编号 ABIN2443989
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Intermolecular Guanine Quadruplex DNA 抗体 (ABIN2443989)
抗原
Intermolecular Guanine Quadruplex DNA
适用
Synthetic
宿主
小鼠
克隆类型
单克隆
标记
非结合性
应用范围
ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (IHC)
克隆位点
1H6
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原理
- Intermolecular Guanine Quadruplex DNA Mouse Monoclonal Antibody (1H6)
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特异性
- The antibody is specific for: guanine quadruplex DNA. * cross-reacts with some other DNA sequences, notably adjacent thymidines in single stranded DNA that are restricted in their movement in G4 structures and denatured DNA fibers.
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纯化方法
- Protein G purified
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亚型
- IgG2b
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute with deionized water. Optimal dilution has to be determined by the user.
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缓冲液
- Lyophilized protein G purified in PBS pH 7.4
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Lyophilized antibodies can be kept at 4°C for up to 3 months and should be kept at -20°C for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80°C) or kept at 4°C for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.
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有效期
- 24 months
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- Intermolecular Guanine Quadruplex DNA
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背景
- G-quadruplexes or G4-DNA is a DNA structural motif that is considered to be functionally important in the mammalian genome for transcriptional regulation, DNA replication and genome stability are nucleic acid. These nucleic acid sequences that are rich in guanine and can form a four-stranded structure. Four guanine bases can associate through Hoogsteen base pairing and are characterized by variable stacks of guanine quartet planes, strand orientation, glycosidic bond angles and stabilizing cations. It may serve important regulatory and structural functions, in addition, it can be the source of genomic instability which may lead to cancer, aging and human genetic diseases
抗原
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