tau 抗体 (pSer208, pSer210)
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Quick Overview for tau 抗体 (pSer208, pSer210) (ABIN2443972)
抗原
See all tau 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer208, pSer210
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原理
- Phospho-Tau (ser 208/210) Rabbit Polyclonal Antibody
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特异性
- The antibody recognizes the human Phospho-Tau protein peptide at the Serines 208 and 210 (Ser 208/210) phosphorylation site. (MW 48-67 kDa)
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纯化方法
- Immunogen affinity purified
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免疫原
- Peptide phosphorylated at Ser 208 and Ser 210
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应用备注
- IHC 1:1000
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- If reconstituted with deionized water in 50 μL: WB: 1:10000, IHC 1:1000. Optimal dilution has to be determined by the user.
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缓冲液
- Lyophilized immunogen affinity purified in PBS pH 7.4
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Lyophilized antibodies can be kept at 4°C for up to 3 months and should be kept at -20°C for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80°C) or kept at 4°C for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.
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有效期
- 24 months
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- tau (tau Protein)
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别名
- tau
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背景
- Tauopathies are a group of diverse dementias and movement disorders which have a common pathological feature in that they all display the presence of intracellular accumulation of abnormal filaments of tau protein. Furthermore, these accumulated tau proteins all display an abnormal phosphorylation pattern that may be disease specific. As an example, Amyotrophic lateral sclerosis (ALS, also referred to as Charcot's disease or Lou Gehrig's disease) is the most common form of progressive motor neuron disease in North America. ALS gradually disables the patient's voluntary motor muscle control until it becomes fatal.
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UniProt
- P10636
抗原
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