UNC13D 抗体 (N-Term)
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Quick Overview for UNC13D 抗体 (N-Term) (ABIN2443930)
抗原
See all UNC13D 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-273, N-Term
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原理
- Munc13-4 Rabbit Polyclonal Antibody
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特异性
- The antibody recognizes the N-terminal of the human Munc13-4 protein (aa 1-273).
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anti-Unc-13 Homolog D (UNC13D) (AA 2-100) antibody
UNC13D 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C7 unconjugated
anti-Unc-13 Homolog D (UNC13D) (Internal Region) antibodyVerified UNC13D 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) (C-Term) antibodyUNC13D 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) (AA 1-1090) antibodyUNC13D 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) (AA 7-172) antibodyUNC13D 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) antibodyUNC13D 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) (AA 1-1090) antibodyUNC13D 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) (C-Term) antibodyVerified UNC13D 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) (C-Term) antibodyUNC13D 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) (AA 891-1090) antibodyUNC13D 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- If reconstituted with deionized water in 50 μL: WB: 1:2000, IP: native conditions. Optimal dilution has to be determined by the user.
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缓冲液
- Lyophilized serum
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Lyophilized antibodies can be kept at 4°C for up to 3 months and should be kept at -20°C for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80°C) or kept at 4°C for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.
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有效期
- 24 months
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- UNC13D (Unc-13 Homolog D (UNC13D))
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别名
- Munc13-4
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背景
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Protein unc-13 homolog D, hMunc13-4, UNC13D, FHL3, HLH3, HPLH3, Munc13-4, unc-13 homolog D
Protein unc-13 homolog D (Munc13-4) is involved in cytotoxic granule exocytosis in lymphocytes. It regulates the assembly of recycling of late endosomal structures which leads to the formation of an endosomal exocytic compartment. It also regulates Ca2+-dependent secretory lysosome exocytosis in mast cells. Munc13-4 is highly expressed in the spleen, thymus and leukocytes and to a lesser extent in the lung and placenta, brain, heart, skeletal muscle and kidney. Defects in Munc13-4 are the cause of familial HL type 3 (FHL3).
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UniProt
- Q70J99
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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