RBBP6 抗体
Our Local Distributor
北京 101111
Quick Overview for RBBP6 抗体 (ABIN2443899)
抗原
See all RBBP6 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- PACT Rabbit Polyclonal Antibody
-
特异性
- The antibody recognizes the human PACT and the mouse homologous RAX.
-
纯化方法
- Immunogen affinity purified
-
-
anti-Retinoblastoma Binding Protein 6 (RBBP6) (AA 1582-1691) antibody
RBBP6 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 5A11 unconjugated
anti-Retinoblastoma Binding Protein 6 (RBBP6) (AA 51-97) antibodyRBBP6 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 6 (RBBP6) (AA 2-150) antibodyRBBP6 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 6 (RBBP6) (AA 1-118) antibodyRBBP6 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 6 (RBBP6) (N-Term) antibodyRBBP6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 6 (RBBP6) (AA 1582-1692) antibodyRBBP6 适用: 人 WB, ELISA, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 5A11 unconjugated
anti-Retinoblastoma Binding Protein 6 (RBBP6) (AA 1-118) antibodyRBBP6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 6 (RBBP6) (AA 395-444) antibodyRBBP6 适用: 人, 小鼠, 大鼠, 猴, Cow, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 6 (RBBP6) (AA 50-100) antibodyRBBP6 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- If reconstituted with deionized water in 50 μL: IP: 10 μg, WB: 1:1000 - 1:3000, IF: 1:500. Optimal dilution has to be determined by the user.
-
缓冲液
- Lyophilized immunogen affinity purified in PBS pH 7.4
-
储存液
- Without preservative
-
储存条件
- 4 °C,-20 °C,-80 °C
-
储存方法
- Lyophilized antibodies can be kept at 4°C for up to 3 months and should be kept at -20°C for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80°C) or kept at 4°C for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.
-
有效期
- 24 months
-
-
- RBBP6 (Retinoblastoma Binding Protein 6 (RBBP6))
-
别名
- PACT
-
背景
-
Interferon-inducible double stranded RNA-dependent protein kinase activator A
The Interferon-inducible double stranded RNA-dependent protein kinase activator, also known as PKR-associated protein X (RAX in mouse) or PACT (in human) is a cellular protein that heterodimerizes with PKR through its double-stranded RNA binding proteins (dsRBDs). PKR is an interferon (IFN)-induced serine-threonine protein kinase that plays a central role in IFN's antiviral and antiproliferative activities. In the absence of viral infections, PACT activates PKR in response to diverse stress signals as serum starvation and treatments with arsenite or peroxide, resulting in the induction of the apoptotic cascade. PACT is expressed in most cell types at a very low abundance, and overexpression of PACT causes PKR activation, leading to eIF2α phosphorylation. PACT has been shown to interact with another DRBM-containing protein, TRBP (TAR RNA binding protein), and form a triple complex with Dicer to facilitate the production of siRNA.
-
UniProt
- O75569
-
途径
- Regulatory RNA Pathways
抗原
-
