CAN 抗体 (small, Subunit B)
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Quick Overview for CAN 抗体 (small, Subunit B) (ABIN2443839)
抗原
See all CAN 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- small, Subunit B
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原理
- Calcineurin Mouse Monoclonal Antibody (VA1)
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特异性
- The antibody recognizes the regulatory β-subunit of calcineurin
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纯化方法
- Protein G purified
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免疫原
- Full lenght bovine protein
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anti-Calcineurin (CAN) (AA 7-301) antibody
CAN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calcineurin (CAN) (AA 21-51) antibodyCAN 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Calcineurin (CAN) (AA 21-51), (N-Term) antibodyCAN 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- If reconstituted with deionized water in 100 μL: WB: 1:2000, ICC: 1:200. Optimal dilution has to be determined by the user.
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缓冲液
- Lyophilized protein G purified in PBS pH 7.4
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Lyophilized antibodies can be kept at 4°C for up to 3 months and should be kept at -20°C for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80°C) or kept at 4°C for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.
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有效期
- 24 months
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- CAN (Calcineurin (CAN))
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别名
- Calcineurin
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背景
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Calcineurin beta-subunit
Within the last 30 years of research the biological roles of calcineurin have progressed from a putative inhibitor of the calmodulin dependent phosphodiesterase to the ground-breaking discovery that it is the target of immunosuppressant drugs such as cyclosporin A. As a serine/threonine protein phosphatase, calcineurin participates in a number of cellular processes and Ca2+ dependent signal transduction pathways. Calcineurin plays a key role in regulating the transcription factor NF-AT during T-cell activation, and in mediating responses of microorganisms to cation stress. Recently, this protein was studied extensively in relation to diseases such as schizophrenia and diabetes.
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UniProt
- P63099
抗原
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