DSCAM 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for DSCAM 抗体 (C-Term) (ABIN2443830)
抗原
See all DSCAM 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 1207-1527, C-Term
-
原理
- Down syndrome cell adhesion molecule (Dscam) Antibody (DS2-176)
-
特异性
- A specific antibody against the chicken Dscam C-terminal region (amino acids 1207 to 1527) .
-
纯化方法
- Protein G purified
-
亚型
- IgG1 kappa
-
-
anti-Down Syndrome Cell Adhesion Molecule (DSCAM) (Internal Region) antibody
Verified DSCAM 适用: 人 ELISA, WB, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-Down Syndrome Cell Adhesion Molecule (DSCAM) (AA 301-400) antibodyDSCAM 适用: 小鼠, 大鼠 ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Down Syndrome Cell Adhesion Molecule (DSCAM) (AA 1548-1597) antibodyDSCAM 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Down Syndrome Cell Adhesion Molecule (DSCAM) (AA 1711-1867) antibodyDSCAM 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Down Syndrome Cell Adhesion Molecule (DSCAM) (AA 361-377), (Extracellular), (N-Term) antibodyDSCAM 适用: 小鼠 WB, IHC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Down Syndrome Cell Adhesion Molecule (DSCAM) (AA 184-271) antibodyDSCAM 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Down Syndrome Cell Adhesion Molecule (DSCAM) (Middle Region) antibodyDSCAM 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, Cow, 豚鼠, Pig WB, IP 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- IHC 1:250
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- If reconstituted with deionized water in 100 μL: IHC 1:250 to 1:500. Optimal dilution has to be determined by the user.
-
缓冲液
- Lyophilized protein G purified in PBS pH 7.4
-
储存液
- Without preservative
-
储存条件
- 4 °C,-20 °C,-80 °C
-
储存方法
- Lyophilized antibodies can be kept at 4°C for up to 3 months and should be kept at -20°C for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80°C) or kept at 4°C for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.
-
有效期
- 24 months
-
-
- DSCAM (Down Syndrome Cell Adhesion Molecule (DSCAM))
-
别名
- Dscam
-
背景
- Down syndrome cell adhesion molecule (Dscam) is a cell adhesion molecule that plays a role in neuronal self-avoidance. It promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Dscam mediates, within retinal amacrine and ganglion cell subtypes, both isoneuronal self-avoidance for creating an orderly dendritic arborization and heteroneuronal self-avoidance to maintain the mosaic spacing between amacrine and ganglion cell bodies. It is the receptor for netrin that is required for axon guidance independently of and in collaboration with the receptor DCC. In spinal cord development, it plays a role in guiding commissural axons during projection and pathfinding across the ventral midline to reach the floor plate upon ligand binding. Dscam enhances netrin-induced phosphorylation of PAK1 and FYN. It mediates intracellular signaling by stimulating the activation of MAPK8 and MAP kinase p38. Dscam interacts with DCC, Netrin-1, PAK1 and RAC1.
-
UniProt
- F1NY98
-
途径
- Regulation of Cell Size
抗原
-
