Aconitase 1 抗体 (full length)
Our Local Distributor
北京 101111
Quick Overview for Aconitase 1 抗体 (full length) (ABIN2443828)
抗原
See all Aconitase 1 (ACO1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- full length
-
原理
- Iron Regulatory Protein 1 (IRP1) Rabbit Polyclonal Antibody
-
特异性
- The antibody recognizes the gull length IRP1 protein
-
免疫原
- Full length protein
-
-
-
-
应用备注
- WB 1:2000
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- If reconstituted with deionized water in 50 μL: WB 1:2000. Optimal dilution has to be determined by the user.
-
缓冲液
- Lyophilized serum
-
储存液
- Without preservative
-
储存条件
- 4 °C,-20 °C,-80 °C
-
储存方法
- Lyophilized antibodies can be kept at 4°C for up to 3 months and should be kept at -20°C for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80°C) or kept at 4°C for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.
-
有效期
- 24 months
-
-
-
: "Iron-responsive element-binding protein 2 plays an essential role in regulating prostate cancer cell growth." in: Oncotarget, Vol. 8, Issue 47, pp. 82231-82243, (2017) (PubMed).
-
-
- Aconitase 1 (ACO1)
-
别名
- Iron Regulatory Protein 1 (IRP1)
-
背景
-
Iron-responsive element-binding proteins, IRE-BP, IRBP, IRP, IFR
The iron regulatory proteins IRP1 and IRP2 are involved in posttranscriptional regulation of cellular iron metabolism by binding to mRNA iron-responsive elements (IREs). IRPs respond to stress mediators, iron concentration and signaling factors, including nitrogen monoxide, cytokines and hydrogen peroxide. IRP-1 is a bifunctional soluble protein that functions as an IRE-binding protein or as the cytoplasmic isoform of aconitase.
-
UniProt
- P21399
-
途径
- Transition Metal Ion Homeostasis
抗原
-