RhoGAP p190 (Catalytic Domain) 抗体
This 兔 多克隆 antibody specifically detects RhoGAP p190 in WB. It exhibits reactivity toward 人.
产品编号 ABIN2443768
发货至:
中国
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Quick Overview for RhoGAP p190 (Catalytic Domain) 抗体 (ABIN2443768)
抗原
RhoGAP p190
适用
人
宿主
兔
克隆类型
多克隆
应用范围
Western Blotting (WB)
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抗原表位
- Catalytic Domain
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原理
- P190RhoGAP Rabbit Polyclonal Antibody
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特异性
- The antibody recognizes the catalytic domain of the human P190RhoGAP protein (fragment of 82 kDa).
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- If reconstituted with deionized water in 50 μL: WB: 1:2000. Optimal dilution has to be determined by the user.
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缓冲液
- Lyophilized serum
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Lyophilized antibodies can be kept at 4°C for up to 3 months and should be kept at -20°C for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80°C) or kept at 4°C for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.
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有效期
- 24 months
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- RhoGAP p190
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背景
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GRLF1, Glucocorticoid Receptor DNA Binding Factor 1
P190RhoGAP, also known as GRLF1 (glucocorticoid receptor DNA binding factor 1) is a Rho family GTPase-activating protein that was identified as a protein that associates with p120RasGAP. P190RhoGAP is a multidomain protein that plays crucial role in regulating actin cytoskeletal rearrangements in axonal pathfinding and stability and in response to growth factor stimulation, integrin engagement, and v-Src transformation. Recently, it has been suggested that p190RhoGAP has also a role in regulating cell proliferation.
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UniProt
- Q9NRY4
抗原
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