Chromogranin A 抗体 (N-Term)
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Quick Overview for Chromogranin A 抗体 (N-Term) (ABIN2443753)
抗原
See all Chromogranin A (CHGA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 4-16, N-Term
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原理
- Chromogranin-A (N-term) Rabbit Polyclonal Antibody
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特异性
- The antibody recognizes an epitope in N-terminal (AA 4-16) of Chromogranine-A
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免疫原
- N-terminal peptide (AA 4-16)
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应用备注
- WB 1:2000
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- If reconstituted with deionized water in 100 μL: WB 1:2000. Optimal dilution has to be determined by the user.
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缓冲液
- Lyophilized serum
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Lyophilized antibodies can be kept at 4°C for up to 3 months and should be kept at -20°C for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80°C) or kept at 4°C for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.
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有效期
- 24 months
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- Chromogranin A (CHGA)
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别名
- Chromogranin-A
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背景
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hCGA, parathyroid secretory protein 1, CHGA
Chromogranin-A is a secreted protein known as a ""prohormone"" which is found in endocrine cells and neurons and may be released upon stimulation. It is thought to be involved in the formation of dense core granules, where it may be processed to form the bioactive peptide serpinin, which is thought to regulate the biogenesis of dense core granules in endocrine cells. Chromogranin-A is used as a biomarker in patients with neuroendocrine tumors. Recent publications show that incomplete processing of Chromogranin-A may be linked to diabetic retinopathy
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UniProt
- P10645
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途径
- Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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