HIP1 抗体 (C-Term)
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Quick Overview for HIP1 抗体 (C-Term) (ABIN2443742)
抗原
See all HIP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Huntingtin-Interacting Protein 1 (HIP1) Rabbit Polyclonal Antibody
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特异性
- The antibody recognizes the C-terminal portion of HIP1
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纯化方法
- Purified
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免疫原
- peptide in C term
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应用备注
- WB 1:500-1:2500,IF 1:10-1:100
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限制
- 仅限研究用
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溶解方式
- If diluted with deionized water in 100 μL: WB 1:500-1:2500, IF 1:10-1:100. Optimal dilution has to be determined by the user.
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缓冲液
- Immunogen affinity purified in glycerol/PBS pH 7.4
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
- Antibodies diluted in glycerol can be kept at 4°C for up to 2 months and should be kept at -20°C for long-term storage (1 year). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. After the maximum long-term storage period (1 year -20°C or 2 months 4°C) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy.
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有效期
- 12 months
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- HIP1 (Huntingtin Interacting Protein 1 (HIP1))
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别名
- Huntingtin-Interacting Protein 1 (HIP1)
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背景
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HIP1
Hungtinton's disease (HD) is an inherited neurodegenerative disorder characterized by the expression of an expanded polyglutamine tract in the protein huntingtin. HIP1 (huntingtin interacting protein 1) binds to normal huntingtin but this interaction is lost in HD. HIP1 also binds to components of clathrin-coated pits and vesicles and is a marker of clathrin-coated membranes. HIP1 expression levels are altered in several types of cancer.
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UniProt
- O00291
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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