NAIF1 抗体
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北京 101111
Quick Overview for NAIF1 抗体 (ABIN2428455)
抗原
See all NAIF1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Antigen affinity purification
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免疫原
- Recombinant protein of human NAIF1
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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注意事项
- Avoid freeze / thaw cycles.
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储存条件
- -20 °C/-80 °C
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储存方法
- Store at -20°C (regular) and -80°C (long term).
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- NAIF1 (Nuclear Apoptosis Inducing Factor 1 (NAIF1))
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别名
- NAIF1
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背景
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Human NAIF1 is located on chromosome 9q34.11 and encodes 327 amino acids with a homeodomain-like region and two nuclear localization signals at its N-terminal region. NAIF1 is conserved across diverse species, including human, mouse, crab-eating macaque, dog, chicken and frog, and shares no obvious homology to any known genes or proteins. NAIF1 was predominantly localized in the nucleus. Overexpression of NAIF1 inhibited cell growth and induced apoptosis. Furthermore, NAIF1 transfection caused both decreases in mitochondrial membrane potential and caspase-3 activation. In summary, NAIF1 is a nuclear protein that induces apoptosis when overexpressed.
Synonyms: C9orf90, bA379C10.2, RP11-379C10.2 -
分子量
- Calculated MW: 35 kDa
抗原
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