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CD300a 抗体 (PE)

This anti-CD300a antibody is a 小鼠 单克隆 antibody detecting CD300a in FACS. Suitable for 人.
产品编号 ABIN238466
发货至: 中国

Quick Overview for CD300a 抗体 (PE) (ABIN238466)

抗原

See all CD300a (CD300A) 抗体
CD300a (CD300A)

适用

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宿主

  • 20
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小鼠

克隆类型

  • 23
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单克隆

标记

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This CD300a antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

MEM-260
  • 特异性

    The antibody reacts with CD300a, a 60 kDa leukocyte transmembrane glycoprotein expressed on human granulocytes, monocytes, neutrophils, NK cells, mast cells and dendritic cells, 25 % of circulating T cells and 15 % of circulating B cells.

    产品特性

    Synonyms: CLM-8, CMRF35-H, CMRF35-H9, CMRF-35-H9, IRC1/IRC2, IRp60, CMRF35-like molecule 8,Inhibitory receptor protein 60, NK inhibitory receptor, CD300 antigen-like family member A

    纯化方法

    Size-Exclusion Chromatography.

    免疫原

    HPB human acute lymphoid leukemia cell line

    亚型

    IgG1
  • 应用备注

    Suitable for Flow Cytometry analysis of human blood cells using 20 μL reagent / 100 μL ofwhole blood or 10^6 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 15 mM Sodium Azide as preservative and 0.2 % (w/v) high-grade BSA (Protease free) as stabilizer.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody in the dark at 2-8 °C. DO NOT FREEZE! Avoid prolonged exposure to light.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    CD300a (CD300A)

    别名

    CD300A / CMRF35H

    背景

    CD300a (CMRF-35H, IRp60) is a non-MHC-specific inhibitory receptor of immunoglobulin superfamily, which contains three immunoreceptor tyrosine-based inhibitory motifs (ITIMs) that associate with SH2-containing phosphatases SHP-1 and SHP-2. CD300a is expressed on many cell types including T cells, NK cells, neutrophils, eosinophils or mast cells. Its triggering inhibits activating signals such as those of IL5, GM-CSF or eotaxin, as well as supresses mast cell degranulation or NK cell cytotoxic activity.Synonyms: CD300 antigen-like family member A, CLM-8, CMRF-35-H9, CMRF35-H, CMRF35-H9, CMRF35-like molecule 8, IRC1/IRC2, IRp60, Inhibitory receptor protein 60, NK inhibitory receptor

    基因ID

    11314

    UniProt

    Q9UGN4

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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