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CD16 抗体

CD16 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-168 unconjugated
产品编号 ABIN238452
发货至: 中国
  • 抗原 See all CD16 抗体
    CD16
    适用
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    宿主
    • 115
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    小鼠
    克隆类型
    • 136
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    单克隆
    标记
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    This CD16 antibody is un-conjugated
    应用范围
    • 133
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    Flow Cytometry (FACS)
    特异性
    The antibody MEM-168 reacts with CD16 antigen (isoform CD16a). CD16a (FcγRIIIA, 50-65 kDa) is a transmembrane form of CD16, expressed on NK-cells, monocytes and macrophages.
    交叉反应 (详细)
    Species reactivity (tested):Human, Non-Human Primates, Porcine
    产品特性
    Synonyms: IgG Fc receptor III-2, Fc-gamma RIII-alpha, FcR-10, CD16a, FCGR3A, FCG3, IGFR3, Fc-gammaRIIIa, FcRIIIa, Fc-gamma RIII, Low affinity immunoglobulin gamma Fc region receptor III-A
    纯化方法
    Gel filtration and Precipitation methods
    免疫原
    Human granulocytes.
    克隆位点
    MEM-168
    亚型
    IgM
    Top Product
    Discover our top product CD16 Primary Antibody
  • 应用备注
    Suitable for Flow Cytometry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS with 15 mM sodium azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    CD16
    别名
    CD16 (CD16 产品)
    背景
    CD16 (FcγRIII) is a 50-80 kDa glycoprotein serving as a low affinity IgG receptor. Human FcγRIII is expressed in two forms FcγRIII-A and -B. FcγRIII-A is a transmembrane protein of monocytes, macrophages, NK cells and a subset of T cells. It is associated with FcεRI-γ subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FcγRIII-A is associated, moreover, with FcεRI-β subunit. Besides IgG, FcεRI-A can be triggered also by oligomeric IgE. FcγRIII-B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a proadhesive phenotype.Synonyms: CD16A, FCG3, FCGR3, FCGR3A, Fc-gamma RIII, Fc-gamma RIII-alpha, Fc-gamma RIIIa, FcR-10, FcRIII, FcRIIIa, IGFR3, IgG Fc receptor III-2, Low affinity immunoglobulin gamma Fc region receptor III-A
    基因ID
    2214
    UniProt
    P08637
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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