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CD4 抗体

This anti-CD4 antibody is a 小鼠 单克隆 antibody detecting CD4 in FACS, WB, IHC (fro), Func 和 EIA. Suitable for 人.
产品编号 ABIN238364
发货至: 中国

Quick Overview for CD4 抗体 (ABIN238364)

抗原

See all CD4 抗体
CD4

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD4 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func), Enzyme Immunoassay (EIA)

克隆位点

13B8-2
  • 特异性

    The CD4 antigen is a monomeric transmembrane glycoprotein with a molecular weight (Mr) of 60 kDa. CD4 Molecule is expressed on a specific subset of peripheral blood T lymphocytes named ''helper/inducer''. The CD4 antige is present on approximately 45 % of peripheral blood lymphocytes (T4 lymphocytes), 80 % of thymocytes and with a lower density of 100 % of monocytes and on some neutrophils.

    产品特性

    Synonyms: T4/Leu-3, T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3

    免疫原

    Human thymocytes

    亚型

    IgG1
  • 应用备注

    Flow cytometry: Studies of CD4 expressing cells. Fluorescence microscopy or Flow cytometry: 2 g/5x10e5 cells/test. Immunohistochemistry: Working dilution 1/25-1/50. Only suitable on cryostat sections or cell smears.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Reconstitute with 1 mL distilled water.

    浓度

    0.2 mg/mL (prior to lyophilization)

    缓冲液

    PBS containing 1 mg/mL BSA as stabilizer without preservatives.

    储存液

    Without preservative

    储存条件

    4 °C/-20 °C

    储存方法

    Store lyophilized (preferably in a desiccator) at 2-8 °C and reconstituted (in aliquots) at-20 °C. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    CD4

    别名

    CD4

    背景

    CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.Synonyms: T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4

    基因ID

    920

    UniProt

    P01730

    途径

    TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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