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s100a4 抗体

S100A4 适用: 人 IHC, FACS 宿主: 小鼠 Monoclonal NJ-4F3 unconjugated
产品编号 ABIN238333
发货至: 中国
  • 抗原 See all s100a4 (S100A4) 抗体
    s100a4 (S100A4) (S100 Calcium Binding Protein A4 (S100A4))
    适用
    • 87
    • 60
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    宿主
    • 73
    • 27
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    小鼠
    克隆类型
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    单克隆
    标记
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    This s100a4 antibody is un-conjugated
    应用范围
    • 87
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    Immunohistochemistry (IHC), Flow Cytometry (FACS)
    纯化方法
    Protein G
    免疫原
    genetic immunisation with cDNA encoding S100 A4
    克隆位点
    NJ-4F3
    亚型
    IgG1
    Top Product
    Discover our top product S100A4 Primary Antibody
  • 应用备注
    Flow cytometry: 1.2 µg/10^6 cells
    CELISA: 1:200 - 1:400
    ELISA: 1:200 - 1:400
    For each application a titration should be performed to determine the optimal concentration.
    限制
    仅限研究用
  • 缓冲液
    PBS, pH 7.2
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C
    储存方法
    short term: 2 °C - 8 °C, long term: -20 °C
  • 抗原
    s100a4 (S100A4) (S100 Calcium Binding Protein A4 (S100A4))
    别名
    S100A4 (S100A4 产品)
    别名
    18A2 antibody, 42A antibody, CAPL antibody, FSP1 antibody, MTS1 antibody, P9KA antibody, PEL98 antibody, 42a antibody, Capl antibody, FSp1 antibody, Mts1 antibody, PeL98 antibody, metastasin antibody, pk9a antibody, S100A4 antibody, P9ka antibody, RNP9KA antibody, S100 calcium binding protein A4 antibody, S100 calcium-binding protein A4 antibody, S100A4 antibody, S100a4 antibody
    背景
    S100 calcium binding protein A4 (S100A4) is a member of the S100 family of calcium-binding proteins that contain two Ca(2+)-binding sites including a canonical EF-hand motif. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells. S100A4 interacts with cytoskeletal proteins and enhances metastasis of several types of cancer cells. It is secreted by unknown mechanisms, thus, paracrinely stimulating a variety of cellular responses, including angiogenesis and neuronal growth. S100A4 has been shown to be a prognostic marker in a number of human cancers, including esophageal-squamous cancers, non-small lung cancers, primary gastric cancers, malignant melanomas, prostate cancers, bladder cancers, and pancreatic carcinomas. The universality of S100A4 expression in a variety of cancers illustrates the potential use of S100A4 as a marker for tumor metastasis and disease progression.
    UniProt
    P26447
    途径
    S100 Proteins
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