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s100a4 抗体

This 小鼠 单克隆 antibody specifically detects s100a4 in IHC 和 FACS. It exhibits reactivity toward 人.
产品编号 ABIN238333
发货至: 中国
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Quick Overview for s100a4 抗体 (ABIN238333)

抗原

See all s100a4 (S100A4) 抗体
s100a4 (S100A4) (S100 Calcium Binding Protein A4 (S100A4))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This s100a4 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Flow Cytometry (FACS)

克隆位点

NJ-4F3
  • 纯化方法

    Protein G

    免疫原

    genetic immunisation with cDNA encoding S100 A4

    亚型

    IgG1
  • 应用备注

    Flow cytometry: 1.2 µg/10^6 cells
    CELISA: 1:200 - 1:400
    ELISA: 1:200 - 1:400
    For each application a titration should be performed to determine the optimal concentration.

    限制

    仅限研究用
  • 缓冲液

    PBS, pH 7.2

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C

    储存方法

    short term: 2 °C - 8 °C, long term: -20 °C
  • 抗原

    s100a4 (S100A4) (S100 Calcium Binding Protein A4 (S100A4))

    别名

    S100A4

    背景

    S100 calcium binding protein A4 (S100A4) is a member of the S100 family of calcium-binding proteins that contain two Ca(2+)-binding sites including a canonical EF-hand motif. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells. S100A4 interacts with cytoskeletal proteins and enhances metastasis of several types of cancer cells. It is secreted by unknown mechanisms, thus, paracrinely stimulating a variety of cellular responses, including angiogenesis and neuronal growth. S100A4 has been shown to be a prognostic marker in a number of human cancers, including esophageal-squamous cancers, non-small lung cancers, primary gastric cancers, malignant melanomas, prostate cancers, bladder cancers, and pancreatic carcinomas. The universality of S100A4 expression in a variety of cancers illustrates the potential use of S100A4 as a marker for tumor metastasis and disease progression.

    UniProt

    P26447

    途径

    S100 Proteins
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