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- 抗原 See all GDF15 抗体
- GDF15 (Growth Differentiation Factor 15 (GDF15))
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抗原表位
- AA 30-194, N-Term
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This GDF15 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Cell-ELISA (cELISA)
- 纯化方法
- Protein G
- 免疫原
- genetic immunisation with cDNA encoding aa30-194 (N-term) of MIC-1 proprotein
- 克隆位点
- ME-6D10
- 亚型
- IgG1
- Top Product
- Discover our top product GDF15 Primary Antibody
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anti-Growth Differentiation Factor 15 (GDF15) (AA 49-308) antibody
GDF15 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (C-Term) antibodyVerified GDF15 适用: 人 WB, ELISA, IHC, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (C-Term) antibody (Biotin)GDF15 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal Biotin
anti-Growth Differentiation Factor 15 (GDF15) (AA 51-79) antibodyGDF15 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 221-308) antibodyGDF15 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 30-308) antibodyGDF15 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (C-Term) antibody (HRP)GDF15 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal HRP
anti-Growth Differentiation Factor 15 (GDF15) (AA 195-308) antibodyGDF15 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 198-308) antibodyGDF15 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 16-143) antibodyGDF15 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Flow cytometry: 1.2 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration. - 说明
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Synonyms: GDF15
- 限制
- 仅限研究用
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- 缓冲液
- PBS, pH 7.2
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C
- 储存方法
- short term: 2 °C - 8 °C, long term: -20 °C
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- 抗原
- GDF15 (Growth Differentiation Factor 15 (GDF15))
- 别名
- MIC-1 (GDF15 产品)
- 别名
- GDF15 antibody, GDF-15 antibody, MIC-1 antibody, MIC1 antibody, NAG-1 antibody, PDF antibody, PLAB antibody, PTGFB antibody, SBF antibody, growth differentiation factor 15 antibody, GDF15 antibody, Gdf15 antibody
- 背景
- Macrophage inhibitory cytokine-1 (MIC-1) is a member of the transforming growth factor-ß superfamily that regulates a wide variety of physiological processes involved in tissue differentiation and maintenance. MIC-1 is synthesized as a 62-kDa intracellular protein, which, after cleavage by a furin like protease, is secreted as a 25-kDa disulphide-linked dimeric protein. Expression of MIC-1 results in inhibition of macrophage activation, regulated by the p53 pathway, in response to pro-inflammatory monokines. MIC-1 is involved in tumour pathogenesis and its measurement can be used as a clinical tool for the diagnosis of a wide range of cancers. It could be a useful marker for aggressive prostate cancer while MIC-1 is upregulated in advanced and more aggressive prostatic tumours.
- UniProt
- Q99988
- 途径
- SARS-CoV-2 Protein Interactome
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