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CEACAM20 抗体

This 小鼠 单克隆 anti-CEACAM20 antibody (Clone HT-12D8) specifically detects CEACAM20 in FACS 和 cELISA. The antibody is reactive with 人 samples.
产品编号 ABIN238330
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CEACAM20 抗体 (ABIN238330)

抗原

CEACAM20 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 20 (CEACAM20))

适用

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宿主

  • 2
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小鼠

克隆类型

  • 2
  • 1
单克隆

标记

  • 3
This CEACAM20 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Cell-ELISA (cELISA)

克隆位点

HT-12D8
  • 纯化方法

    Protein G

    免疫原

    genetic immunisation with cDNA encoding human CEACAM20

    亚型

    IgG1
  • 应用备注

    Flow cytometry: 1.2 µg/10^6 cells
    Immunofluorescence: 1 µg/10^6 cells
    CELISA: 1:200 - 1:400
    For each application a titration should be performed to determine the optimal concentration.

    限制

    仅限研究用
  • 缓冲液

    PBS, pH 7.2

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C

    储存方法

    short term: 2 °C - 8 °C, long term: -20 °C
  • 抗原

    CEACAM20 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 20 (CEACAM20))

    别名

    CEACAM20

    背景

    CEA-related cell adhesion molecule 20 (CEACAM20) belongs to the carcinoembryonic antigen (CEA) gene family. It encodes a putative glycoprotein which is membrane-bound via a transmembrane domain. The CEACAM20 protein contains a single N domain followed by 4 immunoglobulin-like A (A1, A2) and B (B1, B2) domains. Expression of CEACAM20 can be found in tissues of prostate, testis, duodenum and small intestine with highest expression in prostate. The function of CEACAM family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria. High expression of CEACAM20 in tissue of prostate carcinoma and in prostate carcinoma cell lines suggest that CEACAM20 can be used as a tumor marker.

    UniProt

    Q6UY09
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