Prekallikrein 抗体 (Heavy Chain)
Our Local Distributor
北京 101111
Quick Overview for Prekallikrein 抗体 (Heavy Chain) (ABIN236108)
抗原
See all Prekallikrein (PK) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- Heavy Chain
-
特异性
- Recognizes two variants (88 kDa and 85 kDa) of prekallikrein and its activation products kallikrein (88 kDa and 85 kDa), the complexes formed by kallikrein with its endogenous inhibitors C1 inhibitor, alpha-2-macroglobulin and Antithrombin III, and 45 kDa prekallikrein/kallikrein fragment(s). Recognizes prekallikrein and its activation products in human, chimpanzee, rhesus, and baboon plasmas. The epitope for this antibody, located on the prekallikrein/kallikrein heavy chain, is involved in the interaction between prekallikrein and factor XIIa. This antibody inhibits prekallikrein activation in human and rhesus plasmas by approximately 60-80% and 55%, respectively. This antibody does not cross-react with tissue kallikrein.
-
产品特性
- MAb to Prekallikrein Heavy Chain, Monoclonal antibody to Prekallikrein Heavy Chain
-
纯化方法
- Protein G Chromatography. Ascites
-
免疫原
- Purified human plasma prekallikrein
-
亚型
- IgG1
-
-
-
-
应用备注
- Suitable for use in ELISA and Western blot. Note: Prekallikrein activation may occur with repeated freezing/thawing (3x or more) of plasma samples. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS, pH 7.4.
-
储存液
- Without preservative
-
注意事项
-
Avoid multiple freeze/thaw cycles.
Centrifuge product if not completely clear after standing at room temperature.
Prepare working dilution only prior to immediate use. -
储存条件
- -20 °C
-
储存方法
- Upon receipt, aliquot and store at -20 °C.
-
-
- Prekallikrein (PK)
-
别名
- Prekallikrein
抗原
-