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THRA 抗体 (N-Term)

Name: THRA 抗体 (N-Term)
SKU: ABIN233838
Availability: OutOfStock

Rockland 600-401-a38 THRA 适用: 人 WB, ELISA, IHC, IP, FM 宿主: 兔 Polyclonal unconjugated

Western blot using affinity purified anti-THRA antibody shows detection of purified recombinant THRA (lane 1) and THRA present in a 293 cell lysate after transient transfection with THRA (lane 3). (THRA 抗体 (N-Term))

1 image

(2 references)

产品编号 ABIN233838

Supplier Product No.: 600-401-a38

发货至: 中国

Datasheet as PDF

抗原 See all THRA 抗体

THRA (Thyroid Hormone Receptor, alpha (THRA))
抗原表位
16

12

6

3

3

2

1

1

1

1

1

1

1

1

1

1

1
N-Term
适用
79

41

36

8

5

4

4

4

4

4

3

3

2
人
宿主
53

25

1
兔
Compatible Secondaries
克隆类型
55

24
多克隆
标记
38

4

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This THRA antibody is un-conjugated
应用范围
61

26

24

14

13

13

6

3

3

2

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Fluorescence Microscopy (FM)

Supplier Product No.

600-401-a38

Supplier

Rockland

原理

THRA Antibody

交叉反应（详细）

This antibody reacts with human THRA protein.

产品特性

Synonyms: rabbit anti-THRA antibody, rabbit anti-Thyroid hormone receptor alpha antibody, Nuclear receptor subfamily 1 group A member 1, c-erbA-alpha, c-erbA-1, V-erbA-related protein 7, EAR7, ERBA1, NR1A1, THRA1, THRA2

纯化方法

This product was affinity purified from monospecific antiserum by immunoaffinity chromatography.

过滤

Sterile filtered

免疫原

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region near the amino terminus of human THRA isoform 1 protein.
Immunogen Type: Conjugated Peptide

亚型

IgG

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anti-Thyroid Hormone Receptor, alpha (THRA) antibody
THRA 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal H43 unconjugated

anti-Thyroid Hormone Receptor, alpha (THRA) antibody (Alkaline Phosphatase (AP))
THRA 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal H43 Alkaline Phosphatase (AP)

anti-Thyroid Hormone Receptor, alpha (THRA) antibody (HRP)
THRA 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal H43 HRP

anti-Thyroid Hormone Receptor, alpha (THRA) antibody (FITC)
THRA 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal H43 FITC

anti-Thyroid Hormone Receptor, alpha (THRA) antibody (PerCP)
THRA 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal H43 PerCP

anti-Thyroid Hormone Receptor, alpha (THRA) antibody (Atto 594)
THRA 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal H43 Atto 594

anti-Thyroid Hormone Receptor, alpha (THRA) antibody (Atto 488)
THRA 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal H43 Atto 488

anti-Thyroid Hormone Receptor, alpha (THRA) antibody (Biotin)
THRA 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal H43 Biotin

anti-Thyroid Hormone Receptor, alpha (THRA) antibody (PE)
THRA 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal H43 PE

应用备注

Immunohistochemistry Dilution: 1:200
Application Note: This affinity purified antibody has been tested for use in ELISA and western blotting.
Western Blot Dilution: 1:500 - 1:2,000
Immunoprecipitation Dilution: 1:100
ELISA Dilution: 1:300,000
IF Microscopy Dilution: 1:200
Other: User Optimized

限制

仅限研究用
状态

Liquid

浓度

0.89 mg/mL

缓冲液

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

有效期

12 months
Contreras-Jurado, García-Serrano, Martínez-Fernández, Ruiz-Llorente, Paramio, Aranda: "Impaired hair growth and wound healing in mice lacking thyroid hormone receptors." in: PLoS ONE, Vol. 9, Issue 9, pp. e108137, (2015) (PubMed).

Mishra, Zhu, Ge, Cheng: "Adipogenesis is differentially impaired by thyroid hormone receptor mutant isoforms." in: Journal of molecular endocrinology, Vol. 44, Issue 4, pp. 247-55, (2010) (PubMed).
抗原

THRA (Thyroid Hormone Receptor, alpha (THRA))

别名

THRA (THRA 产品)

背景

Background: This antibody is designed, produced, and validated as part of a collaboration with the National Cancer Institute (NCI) and is suitable for Cancer, Immunology and Nuclear Signaling research. Thyroid hormone receptor alpha is a nuclear hormone receptor with high affinity for the hormone triiodo-thyronine. THRA is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having a certain extent of redundancy, may mediate different functions of thyroid hormone. THRA interacts with NCOA3 and NCOA6 co-activators, leading to a strong increase in transcription of target genes. THRA is localized within the nucleus and has been found to exist as 4 isoforms originating from alternative splicing variants. This antibody recognizes THRA isoform 1. Isoform 1 has a distinct C-terminus compared to isoform 2.

基因ID

7067, 40806160

UniProt

P10827-2

途径

Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Maintenance of Protein Location, Skeletal Muscle Fiber Development