TMBIM1 抗体 (N-Term)
(1 reference)
Quick Overview for TMBIM1 抗体 (N-Term) (ABIN233805)
抗原
See all TMBIM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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Supplier Product No.
- 200-401-a57
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Supplier
- Rockland
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原理
- TMBIM1 Antibody
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交叉反应 （详细）
- This antibody is specific for human TMBIM1 protein.
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产品特性
- Synonyms: rabbit anti-TMBIM1 Antibody, Putative uncharacterized protein TMBIM1, Protein lifeguard 3, Protein RECS1 homolog, Transmembrane BAX inhibitor motif-containing protein 1, LFG3, RECS1, PP1201, PSEC0158
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纯化方法
- This product was protein A purified from monospecific antiserum by immunoaffinity chromatography using protein A coupled to agarose beads.
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过滤
- Sterile filtered
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免疫原
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Immunogen: This protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein corresponding to the amino terminus of human TMBIM1 protein.
Immunogen Type: Recombinant Protein
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亚型
- IgG
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anti-Transmembrane BAX Inhibitor Motif Containing 1 (TMBIM1) (AA 1-109) antibody
TMBIM1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane BAX Inhibitor Motif Containing 1 (TMBIM1) (C-Term) antibodyTMBIM1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane BAX Inhibitor Motif Containing 1 (TMBIM1) (C-Term) antibodyTMBIM1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane BAX Inhibitor Motif Containing 1 (TMBIM1) (C-Term) antibodyTMBIM1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane BAX Inhibitor Motif Containing 1 (TMBIM1) (AA 46-95) antibodyTMBIM1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane BAX Inhibitor Motif Containing 1 (TMBIM1) (AA 68-97), (N-Term) antibodyTMBIM1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB32602 unconjugated
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应用备注
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Immunohistochemistry Dilution: 10 μg/mL
Application Note: This protein A purified antibody has been tested for use in ELISA, Immunohistochemistry, and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 35 kDa in size corresponding to TMBIM-1 by western blotting in the appropriate cell lysate or extract. To date this antibody has shown the ability to recognize over-expressed TMBIM1 but not endogenous protein.
Western Blot Dilution: 1:500 - 1:2,000
ELISA Dilution: 1:10,000
Other: User Optimized
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.2 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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: "A shear stress responsive gene product PP1201 protects against Fas-mediated apoptosis by reducing Fas expression on the cell surface." in: Apoptosis : an international journal on programmed cell death, (2010) (PubMed).
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: "A shear stress responsive gene product PP1201 protects against Fas-mediated apoptosis by reducing Fas expression on the cell surface." in: Apoptosis : an international journal on programmed cell death, (2010) (PubMed).
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- TMBIM1 (Transmembrane BAX Inhibitor Motif Containing 1 (TMBIM1))
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别名
- TMBIM1
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背景
- Background: This antibody is designed, produced, and validated as part of a collaboration with the National Cancer Institute (NCI) and is suitable for Cancer, Immunology and Nuclear Signaling research. TMBIM1 (Transmembrane BAX inhibitor motif-containing protein 1) is a member of the 7 TMS (7 transmembrane domains) family of receptors known to mediate the activation of various transcription factors. TMBIM1 is identified as a novel modulator of NF-kB activation. A drosophila homolog of this protein (dNMDA1 with 40 % homology to hTMBIM1) is reported to be unregulated during aging and oxidative stress.
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基因ID
- 64114, 50593008
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UniProt
- Q969X1
抗原
-
